(R)-1-[(1S)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLDI-TERT-BUTYLPHOSPHINE

Product Name(R)-1-[(1S)-2-(DIPHENYLPHOSPHINO)FERROCENYL]ETHYLDI-TERT-BUTYLPHOSPHINE
CAS155830-69-6
MFC32H40FeP2
MW542.45
EINECS
MOL File155830-69-6.mol

Chemical Properties

Melting point	218-220°C (dec.)
alpha	-412° ±15° (c 0.5, CHCl3)
storage temp.	Inert atmosphere,Room Temperature
solubility	Chloroform, Methanol
form	Powder
color	Orange

Safety Information

Risk Statements	20/21/22-36/37/38
Safety Statements	24/25
WGK Germany	3
F	10
HS Code	29319090

MSDS

Provider	Language
ACROS	English
SigmaAldrich	English

Usage And Synthesis

Reaction

Ligand for Palladium-catalyzed amination of aryl halides
Ligand for Rhodium-catalyzed asymmetric alcoholysis and aminolysis of oxabenzonorbornadiene
Ligand for Rhodium-catalyzed asymmetric ring opening of oxabicyclic alkenes with organoboronic acids
Ligand for Copper-catalyzed asymmetric 1,4-hydrosilylations of α,β-unsaturated esters
Ligand for Ruthenium-catalyzed asymmetric hydrogenation of N-sulfonated-α-dehydroamino acids
Ligand for Rhodium-catalyzed asymmetric hydrogenation of enamines
Ligand for Palladium-catalyzed Kumada coupling of aryl and vinyl tosylates
Ligand for Palladium-catalyzed enantioselective synthesis of aryl sulfoxides
Ligand for Rhodium-catalyzed enantioselective insertion of a carbenoid carbon into a C-C bond

Chemical Properties

Orange powder

Uses

It may be used as a ligand in the palladium-catalyzed alkoxycarbonylation of 6-bromo-1,4-benzodioxane with sodium tert-butoxide to form the corresponding tert-butyl ester.

General Description

(R)-1-[(S_P)-2-(Diphenylphosphino)ferrocenyl]ethyldi-tert-butylphosphine (PPF-^tBu) is a chiral ferrocenyl diphosphine ligand.

Preparation Products And Raw materials

Raw materials

Hydrochloric acid Ethyl acetate Dichloromethane Acetic acid Potassium carbonate Acetic anhydride n-Butyllithium Lithium Aluminum Hydride Magnesium Phosphorus trichloride 2-Chloro-2-methylpropane Chlorodiphenylphosphine (R)-(+)-N,N-DIMETHYL-1-FERROCENYLETHYLAMINE