Diisopropyl adipate

At room temperature, finely powdered sodium carbonate (1 mmol, 0.106 g) was mixed with freshly distilled thionyl chloride (1 mmol, 0.120 g) in a 25 mL round-bottom flask. A solution of adipic acid (1 mmol) in isopropanol (5 mL) was slowly added to the resulting powder. The resulting reaction mixture was heated to reflux and stirred for 2 hours under reflux conditions. After the reaction was complete, the reaction mixture was poured into a dilute solution of NaHCO3 (10%) until the pH of the reaction mixture reached 9, and then extracted with CH2Cl2 (15 mL). The organic layer was dried over anhydrous sodium sulfate, and the solvent was evaporated under reduced pressure to obtain diisopropyl adipic acid.

Figure: Synthesis of Diisopropyl Adipate

Diisopropyl adipate is colorless transparent liquid at room temperature and pressure, insoluble in water, soluble in common organic solvents. It has the versatility of an ester and a special aroma.

diisopropyl adipate is a low-viscosity emollient. It increases a preparation’s spreadability.

ChEBI: Diisopropyl adipate is a fatty acid ester and an isopropyl ester.

Non flammable