Basic information Safety Related Supplier

pimagedine

Basic information Safety Related Supplier
pimagedine Basic information
pimagedine Chemical Properties
  • Melting point:182-185 °C (decomp)
  • Boiling point:159.5±23.0 °C(Predicted)
  • Density 1.72±0.1 g/cm3(Predicted)
  • refractive index 1.6660 (estimate)
  • pka11.08±0.70(Predicted)
pimagedine Usage And Synthesis
  • UsesInhibitor (advanced glycosylation end-product formation).
  • DefinitionChEBI: A one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide.
  • Enzyme inhibitorThis substituted hydrazine (FWhydrochloride = 110.55 g/mol; CAS 79-17-4), also named pimagedine, is a strong inhibitor of diamine oxidases as well as nitric oxide synthase. Note that aminoguanidine also inhibits the formation of advanced glycosylation end-products, reportedly by reacting with and trapping Amadori rearrangement-derived fragmentation products in solution. In view of this property, aminoguanidine has often been used to treat complications associated with chronic diabetes. Target(s): amine oxidase (copper-containing), or diamine oxidase; methylamine dehydrogenase; tryptophan tryptophylquinone enzymes; nitric-oxide synthase; b-fructofuranosidase, or invertase; monoamine oxidase, or amine oxidase; histidine decarboxylase; aldose reductase; catalase; formation of advanced glycosylation end products; adenosylmethionine decarboxylase; arginine deaminase; arginine kinase; aspartate aminotransferase; histamine N-methyltransferase.
pimagedine(79-17-4)Related Product Information
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  • Company Name:Shanghai T&W Pharmaceutical Co., Ltd.
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  • Company Name:Macheng jinxin biotechnology co., LTD
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  • Company Name:Dayang Chem (Hangzhou) Co.,Ltd.
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