Methyl 3-hydroxybenzoate

• 3-hydroxybenzene-1,2-dicarbaldehyde
• O-methyl O-[3-methyl-4-(methylthio)phenyl]O-(3-methylcarboxyphenyl) phosphorothioate

In the three-port bottle add 3-hydroxybenzoic acid, methanol and hydroxybenzenesulfonic acid, 3-hydroxybenzoic acid and methanol molar ratio of 1:4, the amount of hydroxybenzenesulfonic acid added to the total mass of the reactants of 8.6%, the three-port bottle left mouth plug wear mouth plugs, the right side of the mouth mounted probe tube (inside the temperature probe), the middle mouth of the air condensate tube through the top of the furnace mouth connected to the outside, respectively, mounted on the water separator, water condensate tube, mixing evenly, and then into the electromagnetic stirrer, placed in the microwave oven, start stirring, stirring speed of 300r/min, start the reaction, the reaction process in a timely manner to release the water distributor within the water, in which the microwave oven microwave radiation power of 150W, the microwave radiation temperature of 85 C, the microwave radiation time of 40min; mixed evenly, and then into the electromagnetic stirrer, placed in the microwave oven, start stirring, and then into the microwave oven, the microwave oven, the microwave oven, the reaction process in a timely manner, the microwave oven, the microwave oven, the microwave oven. Start the reaction, the reaction process in time to release the water separator water;

Reaction 1h after the closure of the power supply, the reaction of the liquid into a clean three-mouth bottle and steam distillation of excess methanol, distillation residue is dumped into a clean beaker, cooled precipitation, washed with 10% sodium carbonate solution to pH 7.0-8.0, pumping, rinsing the filter cake with distilled water, drying, refining to obtain white The solid product is methyl 3-hydroxybenzoate. The yield of methyl 3-hydroxybenzoate was determined to be 84.1%.