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Deoxycorticosterone acetate

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Deoxycorticosterone acetate Basic information
Deoxycorticosterone acetate Chemical Properties
  • Melting point:157°C
  • alpha D20 +168 to +176° (dioxane)
  • Boiling point:421.94°C (rough estimate)
  • Density 1.0415 (rough estimate)
  • refractive index 175 ° (C=1, Dioxane)
  • storage temp. Refrigerator
  • solubility H2O: insoluble
  • form neat
  • Water Solubility 4mg/L(25 ºC)
  • Merck 2901
  • BRN 2570798
  • CAS DataBase Reference56-47-3(CAS DataBase Reference)
Safety Information
  • Safety Statements 22-24/25
  • RIDADR UN 2811
  • WGK Germany 3
  • RTECS HG0525000
  • HazardClass IRRITANT
  • HS Code 2937290000
MSDS
Deoxycorticosterone acetate Usage And Synthesis
  • Chemical PropertiesOff-White Solid
  • UsesAdrenocortical/mineralocorticoid Steroid.
  • brand nameDoca (Organon); Percorten (Novartis) [Name previously used: Deoxycortone.].
  • Purification Methods11-Deoxycorticosterone acetate recrystallises from EtOH as needles or Me2CO/hexane, and sublimes at high vacuum. It is partly soluble in MeOH, Me2CO, Et2O and dioxane but insoluble in H2O. [Reichstein & Euw Helv Chim Acta 23 136 1940, Romo et al. J Am Chem Soc 79 5034 1957; NMR: Shoolery & Rogers J Am Chem Soc 80 5121 1959, Beilstein 8 IV 2195.]
Deoxycorticosterone acetate Preparation Products And Raw materials
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