Basic information Description References Safety Related Supplier
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Polysorbate 20

Basic information Description References Safety Related Supplier
Polysorbate 20 Basic information
Polysorbate 20 Chemical Properties
  • Melting point:98.9 °C (decomp)
  • Boiling point:100 °C
  • Density 1.11 g/mL at 20 °C
  • vapor pressure <1.4 hPa (20 °C)
  • refractive index n20/D 1.468(lit.)
  • FEMA 2915 | POLYSORBATE 20
  • Flash point:>230 °F
  • storage temp.  0-6°C
  • solubility 100 g/L
  • form viscous liquid
  • color Amber
  • Specific Gravity1.090~1.130 (20/20℃)
  • PH6-8 (50g/l, H2O, 20℃)
  • PH Range7
  • Water Solubility 100 g/L
  • Hydrophilic-Lipophilic Balance (HLB)16.7
  • Stability:Stable. Incompatible with strong oxidizing agents.
  • EPA Substance Registry SystemPolysorbate 20 (9005-64-5)
Safety Information
Polysorbate 20 Usage And Synthesis
  • DescriptionTween 20, whose common commercial names includes Alkest TW 20 and Polysorbate 20, is a mild nonionic surfactant formed by the ethoxylation of sorbitan before the addition of lauric acid which is a medium-chain fatty acid found mainly in coconut oil. It is allowed to be used as the emulsifier, detergent, dispersant, solvent and stabilizer, etc. in a number of fields such as pharmaceutical, chemical, food, textile and other industries due to its stability and relative non-toxicity.
    Tween 20 is widely applied in biological techniques and sciences, which can be added to buffers and reagents for immunohistochemistry, such as Western blots and ELISAs, helping to prevent non-specific antibody binding, decrease background staining and enhance reagent spreading. Besides, Tween 20 also has applications in food production as a common food grade additive which are found in many consumables on the market today. It can also be used as a wetting agent in flavored mouth drops such as Ice Drops, in oral or non-gastrointestinal suspensions and in rubber balers in the elastomer industry.
  • References
  • Chemical PropertiesPolysorbate 20 is a mixture of laurate partial esters of sorbitol and sorbitol anhydrides condensed with approximately 20 mole of ethylene oxide (C2H4O) for each mole of sorbitol and its mono- and dianhydrides. It has a faint, characteristic odor and a warm, somewhat bitter taste.
  • Chemical PropertiesYellow liquid
  • UsesPharmaceutic aid (surfactant).
  • Usespolysorbate 20 is a solubilizer, emulsifier, viscosity modifier, and stabilizer of essential oils in water.
  • DefinitionChEBI: A polymer composed of PEG-ylated sorbitan, where the total number of poly(ethylene glycol) units is 20 (w + x + y + z = 20) and a single terminal is capped by a dodecanoyl group.
  • PreparationBy condensing the partial esters of sorbitol and its anhydrides with ethylene oxide to effect an oxyethylene copolymerization at the free hydroxyl groups.
  • brand nameTween 20 (ICI Americas).
  • Safety ProfileModerately toxic by intravenous route. Mddly toxic by ingestion. A human skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.
Polysorbate 20 Preparation Products And Raw materials
Polysorbate 20(9005-64-5)Related Product Information
Polysorbate 20SupplierMore
  • Tel:14749365990 020-36293412
  • Products Intro:Product Name:Polysorbate 20
    Purity:99.99% Package:220kg/
  • Company Name:Shanghai Aladdin Bio-Chem Technology Co.,LTD Gold
  • Tel:400-620-6333 021-20337333-801
  • Products Intro:Product Name:Tween 20
    Purity:CP Package:769RMB/5L
  • Company Name:Zhejiang Lianshuo Biotechnology Co., Ltd. Gold
  • Tel:18616526224
  • Products Intro:Product Name:TWEEN 20, 10% SOLUTION, PEROXIDE-FREE
    Purity:PROTEOMICS GRADE Package:10ML-5PK Remarks:M228
  • Company Name:J & K SCIENTIFIC LTD.
  • Tel:400-666-7788 010-82848833-
  • Products Intro:Product Name:Tween 20
  • Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.
  • Tel:400-660-8290 21-61259100-
  • Products Intro:Product Name:Tween 20 (=Polyoxyethylene Sorbitan Monolaurate)
    Package:25g;500g Remarks:T0543