Enoximone is a phosphodiesterase inhibitor indicated for selective use as a
cardiostimulant in heart transplant patient maintenance. It is currently being investigated
for other indications including acute congestive heart failure.
Enoximone is a phosphodiesterase inhibitor used in the treatment of congestive heart failure and is selective to phosphodiesterase 3. Potent PDE-3 inhibitor.
ChEBI: Enoximone is an aromatic ketone.
Inhibitor of type III phosphodiesterase (PDE3). Increases intracellular cyclic AMP (cAMP) concentrations and enhances myocardial contractility. Also induces concentration-dependent vasodilation in vitro .
Selective phosphodiesterase III (PDE3) inhibitor. Prevents the degradation of cAMP by PDE. Increased cAMP results in enhanced contractility of the heart.
