Basic information Safety Related Supplier
ChemicalBook >  Product Catalog >  Organic Chemistry >  Phosphines >  Diethyl cyanomethylphosphonate

Diethyl cyanomethylphosphonate

Basic information Safety Related Supplier
Diethyl cyanomethylphosphonate Basic information
Diethyl cyanomethylphosphonate Chemical Properties
  • Boiling point:101-102 °C0.4 mm Hg(lit.)
  • Density 1.095 g/mL at 25 °C(lit.)
  • refractive index n20/D 1.434(lit.)
  • Flash point:>230 °F
  • storage temp. Inert atmosphere,2-8°C
  • form Liquid
  • color Clear colorless to light yellow
  • Specific Gravity1.1261.095
  • Water Solubility Miscible with water, chloroform, terahydrofuran, ethyl acetate and methylene chloride.
  • BRN 1772981
  • CAS DataBase Reference2537-48-6(CAS DataBase Reference)
  • NIST Chemistry ReferenceDiethyl cyanomethylphosphonate(2537-48-6)
Safety Information
Diethyl cyanomethylphosphonate Usage And Synthesis
  • Chemical Propertiesclear colorless to light yellow liquid
  • UsesWittig reagent.
  • UsesDiethyl cyanomethyl phosphonate is used as an intermediate in Horner-Emmons reaction for the synthesis of substituted nitriles and their amide and heterocyclic derivatives. It is known as a modified Wittig reagent used in the preparation of alpha, beta-unsaturated nitriles from ketones or aldehydes like 3-hydroxy-3-methylbutanal. It reacts with epoxides and nitrones to prepare cyano-substituted cyclopropanes and aziridines respectively. It is actively involved in the synthesis of alpha-arylated alkanenitriles via reaction with aryl iodides in presence of CuI.
Diethyl cyanomethylphosphonate Preparation Products And Raw materials
Diethyl cyanomethylphosphonate(2537-48-6)Related Product Information
Diethyl cyanomethylphosphonateSupplierMore
  • Company Name:Kingfirst Chemical (Nanjing) Co.,Ltd Gold
  • Tel:+86-025-84522992 84524602 13805186390
  • Company Name:Weifang Mingran Chemical Co., Ltd. Gold
  • Tel:15063661899
  • Company Name:Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd. Gold
  • Tel:18678026865 133-96369453-
  • Company Name:Weifang Siyuan Chemical Co., Ltd. Gold
  • Tel:17663601818 0536-8888106-
  • Company Name:Shanghai F.R. Chemical Technology Co.,Ltd Gold
  • Tel:13516785322 021-52230662-