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2,4-Diamino-6-hydroxypyrimidine

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2,4-Diamino-6-hydroxypyrimidine Basic information
2,4-Diamino-6-hydroxypyrimidine Chemical Properties
Safety Information
  • Hazard Codes Xi
  • Risk Statements 36/37/38
  • Safety Statements 22-24/25-36-26
  • WGK Germany 3
  • Hazard Note Irritant
  • TSCA Yes
  • HS Code 29335995
MSDS
2,4-Diamino-6-hydroxypyrimidine Usage And Synthesis
  • Chemical PropertiesWhite Solid
  • Uses2,4-Diamino-6-hydroxypyrimidine (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis. In HUVEC cells, the IC50 for inhibition of BH4 biosynthesis is about 0.3 mM. DAHP can be used to effectively block NO production in several cell types.[Cayman Chemical]
  • UsesIt stands at the beginning of the enzyme-catalyzed cascade that starts with this seven-carbon carbohydrate and ends with the aromatic amino acids phenylalanine, tyrosine, and tryptophan
  • Purification MethodsIt recrystallises from H2O. [Beilstein 25 III/IV 3642.]
2,4-Diamino-6-hydroxypyrimidine Preparation Products And Raw materials
2,4-Diamino-6-hydroxypyrimidine(56-06-4)Related Product Information
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