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1-Hydroxyethylidene-1,1-diphosphonic acid

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1-Hydroxyethylidene-1,1-diphosphonic acid Basic information
1-Hydroxyethylidene-1,1-diphosphonic acid Chemical Properties
  • Melting point:198~199℃
  • Boiling point:578.8±60.0 °C(Predicted)
  • Density 1.45 (60% aq.)
  • form Powder
  • pka1.35, 2.87, 7.03, 11.3(at 25℃)
  • color white
  • PHpH (1.7→100, 25℃) : 1.3~1.8
  • Water Solubility Soluble in water.
  • Merck 14,3863
  • BRN 1789291
  • Stability:Stable. Incompatible with strong oxidizing agents.
  • InChIKeyDBVJJBKOTRCVKF-UHFFFAOYSA-N
  • CAS DataBase Reference2809-21-4(CAS DataBase Reference)
  • EPA Substance Registry SystemEtidronic acid (2809-21-4)
Safety Information
MSDS
1-Hydroxyethylidene-1,1-diphosphonic acid Usage And Synthesis
  • Chemical Propertieslight beige powder
  • UsesEtidronate (Didronel) is a human protein tyrosine phosphatase inhibitor with IC50 of 0.2 μM.
  • DefinitionChEBI: A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.
  • brand nameDidronel (Millot Laboratories, France); Didronel (Procter & Gamble).
1-Hydroxyethylidene-1,1-diphosphonic acid Preparation Products And Raw materials
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