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Fluorescein isothiocyanate isomer I Structure

Fluorescein isothiocyanate isomer I

Chemical Properties

Melting point >360 °C(lit.)
Boiling point 708.6±60.0 °C(Predicted)
Density  1.3423 (rough estimate)
refractive index  1.5060 (estimate)
storage temp.  2-8°C
solubility  Slightly soluble in DMSO, ethanol, methanol DMF and acetone
form  powder
pka 2.2, 4.4, 6.7(at 25℃)
color  White
PH Range Weak green uorescence (6.0) to strong green uorescence (7.2)
Water Solubility  practically insoluble
Sensitive  Moisture Sensitive
λmax 490nm
BRN  1407295
Stability Stability Stable, but moisture-sensitive. Incompatible with strong oxidizing agents, strong bases, amines, acids.
Major Application Magnetic nanowires, immunoassays, analyzing proteins, identifying chromosomes, Salmonella mosomes, diagnosis of cancer, kidney diseases, detecting pathogens, genes, Salmonella cells, toxoplasmosis, enzyme-mediated nucleic acid cleavage, surface molecules on colorectal cancers, treating cancer, chronic lymphocytic leukemia
Biological Applications Analyzing sugar chain; detecting iodide/iodate or total iodine; detecting/imaging thiols; detecting/quantifying biotin derivatives;16 diagnosing classical Hodgkin lymphoma (CHL) in lymph nodes; cellulose nanocrystals for bioimaging applications; treating neuroinflammation; treating/diagnosing cancer; PEO-PCL-PEO triblock copolymers for topical delivery; polymersomes in biomedical or cosmetic applications;apoptosis assay; as a substrate for measuring heparanase activity, human immunodeficiency virus (HIV-1) proteinase activity, kinase activity, phosphatase activity, β-lactamase activity, transglutaminase (TG2) activity; implantable drug-delivery devicess
InChIKey MHMNJMPURVTYEJ-UHFFFAOYSA-N
CAS DataBase Reference 3326-32-7(CAS DataBase Reference)
EPA Substance Registry System Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dihydroxy-5-isothiocyanato- (3326-32-7)

Safety Information

Hazard Codes  Xn,Xi
Risk Statements  42/43-36/37/38-22
Safety Statements  22-45-36/37/39-26-36/37-36
WGK Germany  3
10
TSCA  Yes
HS Code  29329990

MSDS

Usage And Synthesis

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