(11aR)-(+)-10,11,12,13-Tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-5-bis(R)-1phenylethyl]amine

Reaction

1. Chiral ligands for copper-catalyzed asymmetric allylic alkylation with dialkylzincs.
2. Chiral ligands for copper-catalyzed asymmetric conjugate addition of diethylzinc to enones.
3. Chiral ligands for palladium-catalyzed asymmetric hydrosilylation of styrenes
4. Chiral ligands for copper-catalyzed asymmetric ring-opening of oxabicyclic alkenes with Grignard reagents.
5. Chiral ligands for nickel-catalyzed asymmetric hydrovinylation of α-alkyl vinylarenes.
6. Chiral ligands for iridium-catalyzed asymmetric hydrogenation of cyclic enamines.
7. Chiral ligands for iridium-catalyzed asymmetric hydrogenation of cyclic imines.
8. Chiral ligands for gold-catalyzed asymmetric [2 + 2] cycloaddition reaction.
9. Chiral ligands for rhodium-catalyzed asymmetric hydroacylation of salicylaldehydes to homoallylic sulfides.
10. Chiral ligands for palladium-catalyzed asymmetric carboamination reactions. 

Uses

• A catalyst in the preparation of tricyclic alkaloid (+)-aphanorphine via asymmetric carboamination and FriedelCrafts reaction.
• A ligand in the synthesis of chiral ketones via hydroacylation of olefins using salicylaldehyde derivatives.
• A ligand in the enantioselective synthesis of substituted pyrrolidine derivatives via Pd-catalyzed alkene aminoarylation reactions.