gamma-Butyrolacton Produkt Beschreibung

Gamma Butyrolactone Struktur
96-48-0
  • CAS-Nr.96-48-0
  • Bezeichnung:gamma-Butyrolacton
  • Englisch Name:Gamma Butyrolactone
  • Synonyma:γ-Butyrolacton;gamma-Butyrolacton;1,4-Butanolid;gamma-Oxybutters?urelacton;Tetrahydro-2-furanon;Dihydro-2(3H)-furanon
    GBL;BLO;6480;BLON;c-1070;GBL-EL;CadionGr;gamma-BL;GBL96480;GBL,γ-BLO
  • CBNumber:CB9719491
  • Summenformel:C4H6O2
  • Molgewicht:86.09
  • MOL-Datei:96-48-0.mol
gamma-Butyrolacton physikalisch-chemischer Eigenschaften
  • Schmelzpunkt: :-45 °C (lit.)
  • Siedepunkt: :204-205 °C (lit.)
  • Dichte :1.12 g/mL at 25 °C (lit.)
  • Dampfdichte :3 (vs air)
  • Dampfdruck :1.5 mm Hg ( 20 °C)
  • Brechungsindex :n20/D 1.436(lit.)
  • FEMA  :3291 | 4-HYDROXYBUTANOIC ACID LACTONE
  • Flammpunkt: :209 °F
  • storage temp.  :2-8°C
  • Aggregatzustand :neat
  • Farbe :Clear colorless
  • Säure-Base-Indikators(pH-Indikatoren) :4 at 100 g/l at 20 °C
  • Explosionsgrenze :16%
  • Wasserlöslichkeit :MISCIBLE
  • Merck  :13,1596
  • JECFA Number :219
  • BRN  :105248
  • Stabilität: :Stable. Hygroscopic. Incompatible with strong oxidizing agents, strong acids, strong bases, strong reducing agents.
  • InChIKey :YEJRWHAVMIAJKC-UHFFFAOYSA-N
  • CAS Datenbank :96-48-0(CAS DataBase Reference)
  • NIST chemische Informationen :«gamma»-Butyrolactone(96-48-0)
  • IARC :3 (Vol. 11, Sup 7, 71) 1999
  • EPA chemische Informationen :.gamma.-Butyrolactone (96-48-0)
Sicherheit

Gamma Butyrolactone Chemische Eigenschaften,Einsatz,Produktion Methoden

  • ERSCHEINUNGSBILD FARBLOSE, öLIGE, HYGROSKOPISCHE FLüSSIGKEIT.
  • CHEMISCHE GEFAHREN Reagiert mit Säuren, Basen, Alkoholenund Aminen. Zersetzung beim Verbrennen unter Bildung reizender Rauche.
  • ARBEITSPLATZGRENZWERTE TLV nicht festgelegt (ACGIH 2005).
    MAK nicht festgelegt (DFG 2005).
  • AUFNAHMEWEGE Aufnahme in den Körper durch Inhalation der Dämpfe und durch Verschlucken.
  • INHALATIONSGEFAHREN Nur ungenügende Angaben vorhanden über die Geschwindigkeit, mit der eine gesundheitsschädliche Konzentration in der Luft beim Verdampfen bei 20°C erreicht wird.
  • WIRKUNGEN BEI KURZZEITEXPOSITION WIRKUNGEN BEI KURZZEITEXPOSITION:
    Die Substanz reizt die Augen. Beim Verschlucken sind Auswirkungen auf das Zentralnervensystem mit nachfolgendem Atemversagenmöglich. Exposition kann Bewusstseinstrübung verursachen.
  • LECKAGE Ausgelaufene Flüssigkeit in abdichtbaren Behältern sammeln. Reste mit Sand oder inertem Absorptionsmittel aufnehmen und an einen sicheren Ort bringen. Persönliche Schutzausrüstung: Atemschutzfilter für organische Gase und Dämpfe.
  • R-Sätze Betriebsanweisung: R22:Gesundheitsschädlich beim Verschlucken.
    R36:Reizt die Augen.
  • S-Sätze Betriebsanweisung: S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
    S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
    S39:Schutzbrille/Gesichtsschutz tragen.
  • Beschreibung Dihydro-2(3H)-furanone. An endogenous neuroregulator made from gamma-amino butyrate and the precursor of gamma hydroxybutyrate. It causes selective increase of brain dopamine by inhibiting its release from nerve terminals. The compound has sedative properties at low doses and produces surgical anesthesia at high doses. It is also used as an industrial solvent and precursor.
  • Chemische Eigenschaften γ-Butyrolactone is oily, colorless, clear liquid. It has a faint, sweet, aromatic, slightly buttery odor.
    Gamma-butyrolactone
    γ-Butyrolactone is a lactone. It is hydrolyzed under basic conditions, for example in a sodium hydroxide solution into sodium gamma-hydroxybutyrate, the sodium salt of gamma-hydroxybutyric acid. Under acidic conditions it forms an equilibrium mixture of both compounds. These compounds then may go on to form a polymer.
  • Occurrence Reported found as a constituent in coffee aroma; a volatile flavor component in roasted filberts as well. Also reported found in tomato, potato, soybeans, beans, vinegar, mushrooms, roasted chicken, beef, cider, beer, wine, scallops and clams.
  • Verwenden r-butyrolactone is one kind of important fine chemicalintermediate, simultaneously also is one kind of performance fine highboiling point solvent, ideal antioxidant, plasticizer,extracting agent, absorbent, dispersing agent, solid stain, Coagulation Reagent.
  • Verwenden Intermediate in the synthesis of polyvinylpyrrolidone, DL-methionine, piperidine, phenylbutyric acid, thiobutyric acids. Solvent for polyacrylonitrile, cellulose acetate, methyl methacrylate polymers, polystyrene. Constituent of paint removers, textile aids, drilling oils.
  • Definition ChEBI: A butan-4-olide that is tetrahydrofuran substituted by an oxo group at position 2.
  • synthetische From acetylene and formaldehyde, also from a number of alternative sources; ethylene chlorohydrin, glutamic acid, γ-hydroxybutyric acid solutions, tetrahydrofuran, vinyl-acetic acid.
  • Aroma threshold values Detection: 20 to 50 ppm
  • Taste threshold values Taste characteristic at 75 ppm: milky, creamy with fruity peach-like afternotes.
  • Allgemeine Beschreibung Clear colorless oily liquid with a pleasant odor.
  • Air & Water Reaktionen Hygroscopic. Soluble in water.
  • Reaktivität anzeigen gamma-Butyrolactone can react with oxidizing materials, inorganic acids and bases, alcohols and amines. Rapidly hydrolyzed by bases and slowly hydrolyzed by acids. gamma-Butyrolactone is volatile with steam. . The combination of the lactone, butanol, 2,4-dichlorophenol, and sodium hydroxide in the attempted synthesis of 2,4-dichlorophenoxybutyric acid caused a thermal runaway reaction that eventually exploded, [CISHC Chem. Safety Summ., 1977, 48, 3].
  • Hazard Toxic by ingestion. Questionable carcino- gen.
  • Brandgefahr gamma-Butyrolactone is combustible.
  • Sicherheitsprofil Moderately toxic by ingestion, intravenous, and intraperitoneal routes. An experimental teratogen. Other experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data by skin contact. Mutation data reported. Less acutely toxic than ppropiolactone. Combustible when exposed to heat or flame; can react with oxidizing materials. To fight fire, use foam, alcohol foam, CO2, dry chemical. Potentially explosive reaction with butanol + 2,4 dichlorophenol + sodium hydroxide. When heated to decomposition it emits acrid and irritating fumes.
  • mögliche Exposition Used as a chemical intermediate for making other chemicals, including pesticides, cosmetics, and pharmaceuticals; as a solvent for paint, nail polish removers, and industrial chemicals. Used in electronics, drilling and petroleum industries as a stabilizer and solvent. Used as a flavoring agent in various foods and beverages, including grains and breakfast foods, candy, and alcoholic and nonalcoholic drinks. Drug of abuse: the United States Food and Drug Administration has warned the public not to purchase or consume products, containing gamma-butyrolactone (GBL). FDA has also asked the companies that manufacture these products to voluntarily recall them. The agency has received reports of serious health problems—some that are potentially life-threatening—associated with the use of these products. Although labeled as dietary supplements and marketed under various brand names, these products are illegally marketed unapproved new drugs. False advertising claims include building muscles, improved physical performance, enhanced sex, reduced stress and induced sleep
  • Versand/Shipping Listed by some sources as unregulated. UN2810 Toxic liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1—Poisonous materials, Technical Name Required.
  • läuterung methode Dry the lactone over anhydrous CaSO4, then fractionally distil it. Handle it in a fume cupboard due to its TOXICITY. [Beilstein 17 V 7.]
  • Inkompatibilitäten 4-Butyrolactone is incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, alcohols, amines, strong and inorganic acids, strong bases. Rapidly hydrolyzed by bases and slowly hydrolyzed by acids. It is hygroscopic and volatile with steam. Combustible; vapor may form explosive mixture with air.
  • Waste disposal Use a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. It is inappropriate and possibly dangerous to the environment to dispose of expired or waste drugs and pharmaceuticals by flushing them down the toilet or discarding them to the trash. Household quantities of expired or waste pharmaceuticals may be mixed with wet cat litter or coffee grounds, double-bagged in plastic, discard in trash. Larger quantities shall carefully take into consideration applicable DEA, EPA, and FDA regulations. If possible return the pharmaceutical to the manufacturer for proper disposal being careful to properly label and securely package the material. Alternatively, the waste pharmaceutical shall be labeled, securely packaged and transported by a state licensed medical waste contractor to dispose by burial in a licensed hazardous or toxic waste landfill or incinerator. All federal, state, and local environmental regulations must be observed.
Gamma Butyrolactone Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
gamma-Butyrolacton Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
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96-48-0, Gamma Butyrolactone Verwandte Suche:
  • Gamma-Aminobutyric acid(GABA)
  • 4-Hydroxybutyric acid-gama-lactone
  • GAMMA-BUTYROLACTONE, REAGENTPLUS, >=99%
  • 4-HYDROXYBUTANOIC ACID LACTONE 98+% &
  • GAMMA-BUTYROLACTONE, 99+%
  • T-Butyrolactone
  • CadionGr
  • GAMMA-BUTYROLACTONE,1.0MG/MLINMETHANOL
  • GAMMA-BUTYROLACTONE,REAGENT
  • BUTYROLACTONE,GAMMA-(SG)
  • butanolide
  • (g-)bntyrolactone
  • γ-butyrolactone,4-hydroxybutyricacidlactone;tetrahydro-2-furanone
  • Y-BUTYROLACTONE
  • r-BUTYROLACTONE extrapure
  • GAMMMA-BUTYROLACTONE
  • 2-FURANONE,DIHYDRO
  • BUTYROLACTONES
  • BUTYROLACTON-GAMMA
  • .gamma.-Butyrolacton
  • 2-oxolanone4-butanolide
  • γ-Hydroxybutyric acid lactone, 4-Hydroxybutyric acid lactone, GBL
  • γ-Butyrolactone, γ-Hydroxybutyric acid lactone, 4-Hydroxybutyric acid lactone, GBL
  • 1,4-Lactone
  • -Butyrolactone99.5%
  • 4,5-Dihydrofuran-2(3H)-one
  • Butyrolacyone
  • g-Butyrolactone, synthesis grade
  • gaMMa-Butyrolactone, 99+% 1LT
  • gaMMa-Butyrolactone, Electronic Grade
  • 4-Hydroxybutanoic acid lactone (GBL)
  • gaMMa-Butyrolactone ReagentPlus(R), >=99%
  • 4-Hydroxybutanoic acid lactone, >99.9% (GC)
  • GBL,Gamma-Butyrolactone
  • GBL,γ-BLO
  • γ-Butyrolactone solution
  • <i>γ</i>-Butyrolactone
  • amma-Butyrolactone
  • Gammabutyrolacton (GBL)
  • Natural gamma-Butyrolactone
  • Gamma-Butyrolactone 99.5%
  • γ-Butyrolactone (GBL)
  • 99% Purity Colorless Liquid Gamma-Butyrolactone GBL
  • Gamma-butlrolactione
  • gamma-Butyrolactone GBL CAS: 96-48-0
  • 1-Oxacyclopentan-2-one
  • 2(3H)-dihydrofuranone
  • 2(3H)-Furanone, dihydro-
  • 2(3H)-furanone,dihydro-
  • 2,3,4,5-tetrahydro-2-furanone
  • 2-Oxolanone
  • 2-Oxotetrahydrofuran
  • 3-Hydroxybutyric acid lactone
  • 4,5-dihydro-2(3H)-furanone
  • 4-butanolyde
  • 4-Butonolide
  • 4-Deoxytetronic acid
  • 4-deoxytetronicacid