Isobuttersäure

Bezeichnung:Isobuttersäure

CAS-Nr79-31-2

Englisch Name:Isobutyric acid

CBNumberCB3367722

SummenformelC4H8O2

Molgewicht88.11

MOL-Datei79-31-2.mol

Synonyma

Isobuttersure

Isobuttersäure

2-Methylpropions?ure

Isobuttersäure physikalisch-chemischer Eigenschaften

Schmelzpunkt	-47 °C (lit.)
Siedepunkt	153-154 °C (lit.)
Dichte	0.95 g/mL at 25 °C (lit.)
Dampfdichte	3.04 (vs air)
Dampfdruck	1.5 mm Hg ( 20 °C)
Brechungsindex	n20/D 1.393(lit.)
FEMA	2222 \| ISOBUTYRIC ACID
Flammpunkt	132 °F
storage temp.	Store below +30°C.
Löslichkeit	618g/l
Aggregatzustand	Liquid
pka	4.84(at 20℃)
Farbe	Clear colorless
PH	3.96(1 mM solution);3.44(10 mM solution);2.93(100 mM solution);
Geruch (Odor)	at 1.00 % in propylene glycol. acidic sour cheese dairy buttery rancid
Geruchsart	acidic
Explosionsgrenze	1.6-7.3%(V)
Odor Threshold	0.0015ppm
Wasserlöslichkeit	210 g/L (20 ºC)
Merck	14,5155
JECFA Number	253
BRN	635770
Dielectric constant	2.6（Ambient）
InChIKey	KQNPFQTWMSNSAP-UHFFFAOYSA-N
LogP	1.1 at 25℃
CAS Datenbank	79-31-2(CAS DataBase Reference)
NIST chemische Informationen	Propanoic acid, 2-methyl-(79-31-2)
EPA chemische Informationen	Isobutyric acid (79-31-2)

Sicherheit

Kennzeichnung gefährlicher	Xn
R-Sätze:	21/22
S-Sätze:	23-36/37/39-24/25
RIDADR	UN 2529 3/PG 3
WGK Germany	1
RTECS-Nr.	NQ4375000
F	13
Selbstentzündungstemperatur	824 °F
TSCA	Yes
HazardClass	3
PackingGroup	III
HS Code	29156000
Giftige Stoffe Daten	79-31-2(Hazardous Substances Data)
Toxizität	LD50 orally in Rabbit: 266 mg/kg LD50 dermal Rabbit 475 mg/kg

Gefahreninformationscode (GHS)

Isobutyric acid Chemische Eigenschaften,Einsatz,Produktion Methoden

ERSCHEINUNGSBILD
FARBLOSE FLüSSIGKEIT MIT CHARAKTERISTISCHEM GERUCH.
PHYSIKALISCHE GEFAHREN
Die Dämpfe sind schwerer als Luft.
CHEMISCHE GEFAHREN
Schwache Säure.
ARBEITSPLATZGRENZWERTE
TLV nicht festgelegt (ACGIH 2005).
MAK nicht festgelegt (DFG 2005).
AUFNAHMEWEGE
Aufnahme in den Körper durch Inhalation, über die Haut und durch Verschlucken.
INHALATIONSGEFAHREN
Nur ungenügende Angaben vorhanden über die Geschwindigkeit, mit der eine gesundheitsschädliche Konzentration in der Luft beim Verdampfen bei 20°C erreicht wird.
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION:
Die Substanz verätzt die Augen, die Haut und die Atemwege. ätzend beim Verschlucken.
LECKAGE
Zündquellen entfernen. Ausgelaufene Flüssigkeit in abgedeckten Behältern sammeln. Verschüttete Flüssigkeit mit viel Wasser wegspülen.
R-Sätze Betriebsanweisung:
R21/22:Gesundheitsschädlich bei Berührung mit der Haut und beim Verschlucken.
S-Sätze Betriebsanweisung:
S23:Gas/Rauch/Dampf/Aerosol nicht einatmen(geeignete Bezeichnung(en) vom Hersteller anzugeben).
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
Isobutyric acid is a clear colorless oily liquid with an odor and flavor similar to n-butyric acid. Miscible with water, soluble in ethanol and ether. Prepared via oxidation of isobutyl alcohol.
Physikalische Eigenschaften
Isobutyric Acid is a flavoring agent that is a colorless liquid with a strong, penetrating odor, resembling butter. it is miscible in alcohol, propylene glycol, glycerin, mineral oil, and most fixed oils and soluble in water. it is obtained by chemical synthesis. it is also termed isopropylformic acid.
Occurrence
Isobutyric acid occurs naturally in Ceratonia siliqua L. The gum obtained from the kernels of this species is used as a thickener in the food industry. Reported found in several essential oils: Arnica montana, Roman chamomile, Laurus nobilis, imperatoria, and in carob fruits (Siliqua dulcis); also identified in the essence of Seseli tortuosum, Artemisia transiliensis.
Verwenden
Isobutyric acid is used to prepare esters for flavors and perfumes. It is also used as a disinfecting agent, preservative and tanning agent. It finds applications in textile, varnish and the leather industry. Further, it is used as a lactation stimulant in dairy cattle. In addition to this, it is used in the preparation of tetramethylsuccinic acid and diisopropyl ketone.
synthetische
Isobutyric acid is prepared in a similar way to butyric acid, mainly by direct oxidation of isobutanol and isobutyraldehyde, which is obtained by a direct oxidation reaction with air or oxygen.
Definition
ChEBI: Isobutyric acid is a branched fatty acid comprising propanoic acid carrying a methyl branch at C-2. It has a role as a volatile oil component, a plant metabolite and a Daphnia magna metabolite. It is a branched-chain saturated fatty acid, a methyl-branched fatty acid and a fatty acid 4:0. It is a conjugate acid of an isobutyrate.
Application
Isobutyric acid is mainly used in the synthesis of isobutyric acid esters, such as methyl isobutyrate, propyl ester, isoamyl ester and benzyl ester. It can also be used manufacture of esters for solvents, flavors and perfume bases, disinfecting agent, varnish, plasticizers, deliming hides, tanning agent and used in pharmaceutical. Isobutyric acid has some important derivatives that, in the industry, is actually used for the production of isobutyronitrile intermediates, and then converted to isobutylamidine hydrochloride that is the raw materials of pesticide diazinon.
Aroma threshold values
Detection: 10 ppb to 9.5 ppm; aroma characteristics at 10 ppm: acidic pungent, dairy buttery and cheesy with fruity undertones.
Taste threshold values
Taste characteristics at 15 ppm: acidic, sour dairy, creamy, cheese, cultured dairy nuance.
Allgemeine Beschreibung
Isobutyric acid appears as a colorless liquid with a light odor of rancid butter. Flash point 132°F. Density 7.9 lb / gal. Corrosive to metals and tissue.
Air & Water Reaktionen
Flammable. Water soluble
Reaktivität anzeigen
Isobutyric acid corrodes aluminum and other metals. Flammable hydrogen gas may accumulate in enclosed spaces in which this reaction has taken place [USCG, 1999].
Hazard
Toxic by ingestion, strong irritant to tissue.
Health Hazard
Inhalation causes irritation of nose and throat. Ingestion causes irritation of mouth and stomach. Contact with eyes or skin causes irritation.
Brandgefahr
Flammable/combustible material. May be ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
Biochem/physiol Actions
Odor at 10 ppm
Synthese
The preparation of isobutyric acid is similar with butyric acid, which is performed by the direct oxidation of isobutyl alcohol and isobutyraldehyde. Isobutyric acid can be directly generated from the oxidation of isobutyraldehyde in air or oxygen. Other manufacturing methods have isobutyronitrile hydrolysis and methacrylic acid hydrogenation. The oxidation of 2-methyl-1-nitropropane to prepare isobutyric acid can also obtain a higher yield. The purification of Isobutyric acid can be realized by azeotropic distillation with water, and anhydrous isobutyric acid can be obtained by the extractive distillation from carbon tetrachloride. Propylene and formic acid ester can react at 50 °C with the catalysis of hydrofluoric acid to generate methyl isobutyrate and propyl isobutyrate.
läuterung methode
Distil the acid from KMnO4, then redistil it from P2O5. [Beilstein 2 H 288, 2 I 126, 2 II 257, 2 III 637, 2 IV 843.]

Isobutyric acid Upstream-Materialien And Downstream Produkte

Isobuttersäure Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

79-31-2, Isobutyric acid Verwandte Suche:

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