Cortison-21-acetat Produkt Beschreibung

Cortisone acetate Struktur
50-04-4
  • CAS-Nr.50-04-4
  • Bezeichnung:Cortison-21-acetat
  • Englisch Name:Cortisone acetate
  • Synonyma:Cortison-21-acetat
    artriona;cortelan;cortisyl;ricortex;NSC 49420;cortistab;biocortacetate;cortoneacetate;irisoneacetate;cortogenacetate
  • CBNumber:CB9277612
  • Summenformel:C23H30O6
  • Molgewicht:402.48
  • MOL-Datei:50-04-4.mol
Cortison-21-acetat physikalisch-chemischer Eigenschaften
  • Schmelzpunkt: :237-240 °C(lit.)
  • alpha  :D25 +164° (c = 0.5 in acetone); D25 +208 to +217° (dioxane)
  • Brechungsindex :212 ° (C=1, MeOH)
  • storage temp.  :2-8°C
  • Löslichkeit :Practically insoluble in water, freely soluble in methylene chloride, soluble in dioxan, sparingly soluble in acetone, slightly soluble in ethanol (96 per cent) and in methanol.
  • Aggregatzustand :neat
  • Merck  :14,2539
  • BRN  :2067543
  • Stabilität: :Stable. Incompatible with strong oxidizing agents.
  • CAS Datenbank :50-04-4(CAS DataBase Reference)
  • EPA chemische Informationen :Pregn-4-ene-3,11, 20-trione, 21-(acetyloxy)-17-hydroxy- (50-04-4)
Sicherheit
  • S-Sätze: :22-36/37-24/25
  • WGK Germany  :3
  • RTECS-Nr. :GM9140000
  • HS Code  :32041200

Cortisone acetate Chemische Eigenschaften,Einsatz,Produktion Methoden

  • S-Sätze Betriebsanweisung: S22:Staub nicht einatmen.
    S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
  • Chemische Eigenschaften solid
  • Verwenden Cortisone Acetate is a glucocorticoid. Cortisone Acetate is an antiinflammatory agent. Cortisone Acetate is bioavailable and readily converted to the therapeutically active form, Hydrocotisone (H71461 5).
  • Allgemeine Beschreibung Cortisone acetate, 21-(acetyloxy)-17-hydroxypregn-4-ene-3,11,20-trione, is the 21-acetate of naturally occurring cortisone with good systemicanti-inflammatory activity and low-to-moderate salt-retentionactivity after its in vivo conversion to hydrocortisoneacetate. This conversion is mediated by 11β-hydroxysteroiddehydrogenase. It is used for the entire spectrum of uses discussedpreviously under the heading, “Therapeutic Uses ofAdrenal Cortex Hormones”—collagen diseases, Addisondisease, severe shock, allergic conditions, chronic lymphocyticleukemia, and many other indications. Cortisone acetateis relatively ineffective topically, mainly because itmust be reduced in vivo to hydrocortisone. Its plasma halflifeis only about 30 minutes, compared with 90 minutes to3 hours for hydrocortisone.
  • läuterung methode Crystallise -1cortisone-21-acetate from acetone or CHCl3. The UV has 15,800 M-1cm at 238nm in dioxane. [Sarett J Biol Chem 162 601 1946, Beilstein 8 III 4058, 5 IV 3481.]
Cortisone acetate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Cortison-21-acetat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
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50-04-4, Cortisone acetate Verwandte Suche:
  • 11,20-trione,17,21-dihydroxy-pregn-4-ene-21-acetate
  • 11-dehydro-17-hydroxycorticosterone-21-acetate
  • 11-dehydro-17-hydroxycorticosteroneacetate
  • 17,21-dihydroxypregn-4-ene-3,11,20-trioneacetate
  • KENDALL'S COMPOUND 'E' ACETATE
  • CORTISONE 21-ACETATE
  • CORTISONE ACETATE
  • DELTA4-PREGNEN-17ALPHA-21-DIOL-3, 11, 20-TRIONE-21-ACETATE
  • ACETIC ACID 2-((8S,9S,10R,13S,14S,17R)-17-HYDROXY-10,13-DIMETHYL-3,11-DIOXO-2,3,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-17-YL)-2-OXO-ETHYL ESTER
  • 4-PREGNEN-17ALPHA,21-DIOL-3,11,20-TRIONE ACETATE
  • 4-PREGNEN-17,21-DIOL-3,11,20-TRIONE 21-ACETATE
  • 4-PREGNENE-17ALPHA,21-DIOL-3,11,20-TRIONE 21-ACETATE
  • 17ALPHA,21-DIHYDROXY-4-PREGNENE-3,11,20-TRIONE 21-ACETATE
  • 17,21-DIHYDROXYPREGN-4-ENE-3,11,20-TRIONE 21 ACETATE
  • 21-acetoxypregnen-17a-ol-3,11,20-trione
  • 21-Acetoxypregnen-17alpha-ol-3,11,20-trione
  • Cortisoneacetate,99%
  • Cortison Acetate
  • CORTISONE ACETATE CRYSTALLINE
  • CORTISONE-21-ACETATE, PH EUR
  • Pregn-4-ene-3,11,20-trione, 21-(acetyloxy)-17-hydroxy-
  • CORTISONEACETATE,MICRONIZED,USP
  • CORTISONEACETATE,POWDER,USP
  • 21-Acetoxy-17-hydroxypregn-4-ene-3,11,20-trione
  • 21-Acetoxy-17α-hydroxy-3,11,20-triketopregnene-4
  • 21-Acetoxy-17α-hydroxypregn-4-ene-3,11,20-trione
  • 4-Pregnene-17a,21-diol-3,11,20-trione 21-acetate
  • Cortisone, 21-acetate (8CI)
  • Cortisyl Artriona
  • NSC 49420
  • Cortisone acetate, 98.5%
  • 17-hydroxy-3,11,20-trioxopregn-4-en-21-yl acetate
  • Cortisone acetate (Cortisone 21-acetate)
  • 20-trione,21-(acetyloxy)-17-hydroxy-pregn-4-ene-11
  • 21-(acetyloxy)-17-hydroxypregn-4-ene-3,11,20-trione
  • 21-acetoxy-17,alpha-hydroxy-3,11,20-triketopregnene-4
  • 21-acetoxy-17,alpha-hydroxypregn-4-ene-3,11,20-trione
  • acetatecortisone
  • artriona
  • biocortacetate
  • compoundeacetate
  • cortelan
  • cortisonemonoacetate
  • cortistab
  • cortisyl
  • cortogenacetate
  • cortoneacetate
  • irisoneacetate
  • ricortex
  • Pregn-4-ene-3,11,20-trione, 17,21-dihydroxy-, 21-acetate (7CI)
  • 17α,21-Dihydroxy-4-pregnene-3,11,20-trione 21-acetate, 21-Acetoxy-4-pregnen-17α-ol-3,11,20-trione, 4-Pregnene-17α,21-diol-3,11,20-trione 21-acetate
  • 17α,21-Dihydroxy-4-pregnene-3,11,20-trione 21-acetate, 21-Acetoxy-4-pregnen-17α-ol-3,11,20-trione, 4-Pregnene-17α,21-diol-3,11,20-trione 21-acetate, Cortisoni acetas
  • 17,21-dihydroxypregn-4-ene-3,11,20-trione acetat
  • Cortisone Acetate (150 mg)
  • Cortison phosphate
  • Cortone 21-Acetate
  • IMp. A (EP): Hydrocortisone Acetate
  • CORTISONE ACETATE ONISED