Isotretinoin
Bezeichnung:Isotretinoin
CAS-Nr4759-48-2
Englisch Name:Isotretinoin
CBNumberCB6222631
SummenformelC20H28O2
Molgewicht300.44
MOL-Datei4759-48-2.mol
Synonyma
Isotretinoin
Isotretinoin physikalisch-chemischer Eigenschaften
Schmelzpunkt | 172-175 °C (lit.) |
Siedepunkt | 381.66°C (rough estimate) |
Dichte | 1.0597 (rough estimate) |
Brechungsindex | 1.4800 (estimate) |
storage temp. | -20°C |
Löslichkeit | Practically insoluble in water, soluble in methylene chloride, slightly soluble in ethanol (96 per cent). It is sensitive to air, heat and light, especially in solution. Carry out all operations as rapidly as possible and avoid exposure to actinic light; use freshly prepared solutions. |
pka | 4.76±0.33(Predicted) |
Aggregatzustand | Fine Crystalline Powder |
Farbe | Yellow-orange to orange |
Wasserlöslichkeit | insoluble |
maximale Wellenlänge (λmax) | 354nm(EtOH)(lit.) |
Merck | 14,5228 |
Stabilität | Stable, but probably air and light sensitive. Combustible. Incompatible with strong oxidizing agents. |
InChIKey | SHGAZHPCJJPHSC-YCNIQYBTSA-N |
CAS Datenbank | 4759-48-2(CAS DataBase Reference) |
EPA chemische Informationen | Isotretinoin (4759-48-2) |
Kennzeichnung gefährlicher | T |
R-Sätze: | 61-36/37/38-20/21/22 |
S-Sätze: | 53-26-36/37/39-45-37/39 |
WGK Germany | 3 |
RTECS-Nr. | VH6440000 |
TSCA | Yes |
HS Code | 29362100 |
Giftige Stoffe Daten | 4759-48-2(Hazardous Substances Data) |
Toxizität | LD50 (20 day) in mice, rats (mg/kg): 904, 901 i.p.; 3389, >4000 orally (Kamm) |