N-Phenyl-bis(trifluoromethanesulfonimide)

Bezeichnung:N-Phenyl-bis(trifluoromethanesulfonimide)

CAS-Nr37595-74-7

Englisch Name:N-Phenyl-bis(trifluoromethanesulfonimide)

CBNumberCB5289550

SummenformelC8H5F6NO4S2

Molgewicht357.25

MOL-Datei37595-74-7.mol

N-Phenyl-bis(trifluoromethanesulfonimide) physikalisch-chemischer Eigenschaften

Schmelzpunkt	100-102 °C(lit.)
Siedepunkt	305.3±52.0 °C(Predicted)
Dichte	1.766±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
Löslichkeit	Soluble in methanol. Slightly soluble in chloroform and ethyl acetate.
pka	-13.12±0.50(Predicted)
Aggregatzustand	Crystals or Crystalline Powder
Farbe	White or colorless
Sensitive	Moisture Sensitive
BRN	1269141
Stabilität	Moisture Sensitive
InChI	InChI=1S/C8H5F6NO4S2/c9-7(10,11)20(16,17)15(6-4-2-1-3-5-6)21(18,19)8(12,13)14/h1-5H
InChIKey	DIOHEXPTUTVCNX-UHFFFAOYSA-N
SMILES	C(F)(F)(F)S(N(C1=CC=CC=C1)S(C(F)(F)F)(=O)=O)(=O)=O
CAS Datenbank	37595-74-7(CAS DataBase Reference)
NIST chemische Informationen	N-phenyltrifluoromethanesulfonimide(37595-74-7)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-36
WGK Germany	3
F	21
TSCA	No
HazardClass	IRRITANT
HS Code	29242100

Gefahreninformationscode (GHS)

N-Phenyl-bis(trifluoromethanesulfonimide) Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
N-Phenylbis(trifluoromethanesulfonimide) acts as a mild triflating reagent as well as a transparent strong electron-withdrawing p-type dopant in carbon nanotubes. It is also employed as a reactant for the preparation of amphoteric alfa-boryl aldehydes. It plays an important role in the enantioselective synthesis of the core ring skeleton of leucosceptroids A-D and in steroselective sulfoxidation.
Chemische Eigenschaften
white to off-white crystalline powder
Verwenden
Acts as a transparent strong electron-withdrawing p-type dopant in carbon nanotubes

Reactant for:
Synthesis of amphoteric alpha-boryl aldehydes
Enantioselective synthesis of core ring skeleton of leucosceptroids A-D
Stereoselective synthesis of monoamine reuptake inhibitor NS9544 acetate
Stereoselective sulfoxidation
Verwenden
N-Phenylbis(trifluoromethanesulfonamide) is used in the enantioselective synthesis of β-amino acids via the Mannich reaction. Used in the synthesis of sphingosine 1-phosphate-1 receptor agonists useful in pharmaceutical application.
Synthese
Add methylene chloride, aniline, 4-dimethylaminopyridine (DMAP), and triethylamine to a reactor equipped with a thermometer, distillation device, and mechanical stirring. When the vacuum of the reactor is evacuated to -0.095MPa and cooled to -40°C, trifluoromethanesulfonyl fluoride gas is introduced and then stirred at -20°C ~ 0°C and 0.02MPa ~ 0.1MPa reaction pressure, and react for 6 hours Finally, the excess trifluoromethanesulfonyl fluoride gas in the reactor is released and collected by cooling. After the inside of the reactor is brought to normal pressure, 500 mL of water is added, and the liquid is separated. A light yellow solid is obtained after the organic phase is heated to 40°C and methylene chloride is distilled. The light yellow solid is recrystallized with toluene to obtain 650g of white crystal N-Phenyl-bis(trifluoromethanesulfonimide).

N-Phenyl-bis(trifluoromethanesulfonimide) Upstream-Materialien And Downstream Produkte

N-Phenyl-bis(trifluoromethanesulfonimide) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

37595-74-7, N-Phenyl-bis(trifluoromethanesulfonimide) Verwandte Suche:

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