Ethylglycinathydrochlorid

Bezeichnung:Ethylglycinathydrochlorid

CAS-Nr623-33-6

Englisch Name:Glycine ethyl ester hydrochloride

CBNumberCB5275670

SummenformelC4H9NO2.ClH

Molgewicht139.58

MOL-Datei623-33-6.mol

Synonyma

Ethylglycinathydrochlorid

Ethylglycinathydrochlorid physikalisch-chemischer Eigenschaften

Schmelzpunkt	145-146 °C(lit.)
Dichte	1.371 g/cm3
storage temp.	2-8°C
Löslichkeit	>1000 g/L (20 °C)
Aggregatzustand	Crystalline Powder
pka	pK1:7.66(＋1) (25°C)
Farbe	White
Geruch (Odor)	Odorless
PH	2.9 (10g/l, H2O, 20℃)
Wasserlöslichkeit	>1000 g/L (20 ºC)
Sensitive	Hygroscopic
BRN	3594034
InChIKey	TXTWXQXDMWILOF-UHFFFAOYSA-N
CAS Datenbank	623-33-6(CAS DataBase Reference)
EPA chemische Informationen	Glycine, ethyl ester, hydrochloride (623-33-6)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	41-36/37/38
S-Sätze:	26-39-24/25-37/39
WGK Germany	3
RTECS-Nr.	MC0525000
TSCA	Yes
HS Code	29224995

Gefahreninformationscode (GHS)

Glycine ethyl ester hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R41:Gefahr ernster Augenschäden.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S39:Schutzbrille/Gesichtsschutz tragen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
Crystalline
Verwenden
As a Glycine (G615990) ester, Glycine ethyl ester hydrochloride can be used as parakeratosis inhibitor and external composition for skin.
Verwenden
Glycine ethyl ester (GEE) is used in conjunction with N-(3-Dimethylaminopropyl)-N?-ethylcarbodiimide (EDC) for carboxyl-foot printing studies of proteins. The GEE/EDC protocol effects specific derivatization of glutamate and aspartate carboxyl side chains on intact proteins. This reaction is readily done under aqueous conditions at physiological pH. It is mainly used as a pharmaceutical raw material. Glycine ethyl ester hydrochloride is an important intermediate for preparing chrysanthemic acid or two chlorine chrysanthemic acid and is mainly used in the synthesis of anti-inflammatory drugs, but also can be used for the synthesis of four imidazole acetic acid.
Synthese
A production method for glycine ethyl ester hydrochloride:First add dehydrated ethanol in 1# reactor, pass into anhydrous hydrogen chloride to obtain hydrochloric acid-ethanol solution; Add a certain amount of triethyl orthoformate and glycine and hydrochloric acid-ethanol solution in 2# reactor, in the Reaction under action; after the reaction is complete, distill and recover ethanol and ethyl formate; then add alcohol-ether mixture, wash, filter, concentrate, recrystallize, and vacuum dry to obtain ethyl glycine hydrochloride.
läuterung methode
Crystallise it from absolute EtOH or EtOH/Et2O. [Marvel Org Synth Coll Vol II 310 1943, Beilstein 4 II 780, 4 III 3 75.]

Glycine ethyl ester hydrochloride Upstream-Materialien And Downstream Produkte

Ethylglycinathydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

623-33-6, Glycine ethyl ester hydrochloride Verwandte Suche:

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