Diazoessigsäure-ethylester

Bezeichnung:Diazoessigsäure-ethylester

CAS-Nr623-73-4

Englisch Name:Ethyl diazoacetate

CBNumberCB9241343

SummenformelC4H6N2O2

Molgewicht114.1

MOL-Datei623-73-4.mol

Synonyma

Ethyldiazoacetat

Diazoessigsäure-ethylester

Diazoessigsäure-ethylester physikalisch-chemischer Eigenschaften

Schmelzpunkt	-22 °C (lit.)
Siedepunkt	140-141 °C/720 mmHg (lit.)
Dichte	1.085 g/mL at 25 °C (lit.)
Brechungsindex	n20/D 1.46(lit.)
Flammpunkt	115 °F
storage temp.	2-8°C
Löslichkeit	Chloroform (Slightly), DMSO (Soluble), Hexane (Slightly), Methanol (Slightly)
Aggregatzustand	Oil
Farbe	Light Yellow to Orange
Merck	13,3021
BRN	107654
NIST chemische Informationen	Ethyl diazoacetate(623-73-4)

Sicherheit

Kennzeichnung gefährlicher	Xn,F
R-Sätze:	5-10-22-40-67-65-48/20-38-11-63
S-Sätze:	36/37-62-16
RIDADR	UN 1993 3/PG 3
WGK Germany	3
RTECS-Nr.	AG5775000
HazardClass	3.2
PackingGroup	III
HS Code	29270000

Gefahreninformationscode (GHS)

Ethyl diazoacetate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R5:Beim Erwärmen explosionsfähig.
R10:Entzündlich.
R22:Gesundheitsschädlich beim Verschlucken.
R40:Verdacht auf krebserzeugende Wirkung.
S-Sätze Betriebsanweisung:
S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
Chemische Eigenschaften
Liquid.
Verwenden
Reagent for ruthenium-catalyzed asymmetric cyclopropanation of alkenes.1
Verwenden
New Diazoacetate Formulations
Hazard
Flammable liquid that explodes when heated.
Sicherheitsprofil
Poison by ingestion and intravenous routes. Questionable carcinogen with experimental carcinogenic and tumorigenic data. Can explode. Explodes on contact with tris(dimethy1amino) antimony. When heated to decomposition it emits toxic fumes of NOx. See also ESTERS.
läuterung methode
It is a very volatile yellow oil with a strong pungent odour. EXPLOSIVE [distillation even under reduced pressure is dangerous and may result in an explosion — TAKE ALL THE NECESSARY PRECAUTIONS IF DISTILLATION IS TO BE CARRIED OUT]. It explodes in contact with conc H2SO4-trace acid causes rapid decomposition. It is slightly soluble in H2O, but is miscible with EtOH, *C6H6, pet ether and Et2O. To purify, dissolve it in Et2O [using CH2Cl2 instead of Et2O, protects the ester from acid], wash it with 10% aqueous Na2CO3, dry (MgSO4), filter and repeat as many times as possible until the Et2O layer loses its yellow colour, then remove the solvent below 20o (vacuum). Note that prolonged heating may lead to rapid decomposition and low yields. It can also be purified by steam distillation under reduced pressure but with considerable loss in yield. Place the residual oil in a brown bottle, keep below 10o, and use as soon as possible without distilling. For preparing esters usually the ethereal solution is used directly without purification. [Womack & Nelson Org Synth Coll Vol III 392 1955, UV: Miller & White J Am Chem Soc 79 5974 1957, Fieser 1 367 1967, Beilstein 3 IV 1495.]

Ethyl diazoacetate Upstream-Materialien And Downstream Produkte

Diazoessigsäure-ethylester Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

623-73-4, Ethyl diazoacetate Verwandte Suche:

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