Carbofuran (ISO) Produkt Beschreibung

Carbofuran Struktur
1563-66-2
  • CAS-Nr.1563-66-2
  • Bezeichnung:Carbofuran (ISO)
  • Englisch Name:Carbofuran
  • Synonyma:Carbofuran;Carbofuran (ISO);2,3-Dihydro-2,2-dimethylbenzofuran-7-yl methylcarbamat;2,3-Dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamat;2,2-Dimethyl-2,3-dihydro-7-benzofuranyl-N-methylcarbamat
    Nex;yalox;d1221;mef248;BURAON;Yaltox;brifur;D 1221;oms864;bay 70
  • CBNumber:CB4322944
  • Summenformel:C12H15NO3
  • Molgewicht:221.25
  • MOL-Datei:1563-66-2.mol
Carbofuran (ISO) physikalisch-chemischer Eigenschaften
  • Schmelzpunkt: :150-153 °C(lit.)
  • Siedepunkt: :200°C
  • Dichte :1.18
  • Dampfdruck :2 x 10-5 mmHg at 33 °C (quoted, Verschueren, 1983)
  • Brechungsindex :1.5200 (estimate)
  • storage temp.  : 0-6°C
  • Löslichkeit :Methylene chloride (>200 g/L), 2-propanol (20–50 g/L) (Worthing and Hance, 1991)
  • Aggregatzustand :Powder
  • Farbe :White, brown
  • Wasserlöslichkeit :Slightly soluble. 0.07 g/100 mL
  • Merck  :13,1813
  • BRN  :1428746
  • Henry's Law Constant :3.88 (x 10-8 atm?m3/mol)at 30 °C (approximate - calculated from water solubility and vapor pressure)
  • Expositionsgrenzwerte :OSHA PEL: TWA 0.1 mg/m3; ACGIH TLV: TWA 0.1 mg/m3.
  • CAS Datenbank :1563-66-2(CAS DataBase Reference)
  • NIST chemische Informationen :Carbofurane(1563-66-2)
  • EPA chemische Informationen :7-Benzofuranol, 2,3-dihydro-2,2-dimethyl-, methylcarbamate(1563-66-2)
Sicherheit

Carbofuran Chemische Eigenschaften,Einsatz,Produktion Methoden

  • ERSCHEINUNGSBILD FARBLOSE KRISTALLE.
  • CHEMISCHE GEFAHREN Zersetzung beim Erhitzen unter Bildung giftiger Rauche mit Stickstoffoxiden.
  • ARBEITSPLATZGRENZWERTE TLV: (Einatembare Fraktion, als Dampf oder Aerosol) 0.1 mg/m? Krebskategorie A4 (nicht klassifizierbar als krebserzeugend für den Menschen); BEI vorhanden; (ACGIH 2005).
    MAK nicht festgelegt (DFG 2005).
  • AUFNAHMEWEGE Aufnahme in den Körper durch Inhalation und durch Verschlucken.
  • INHALATIONSGEFAHREN Verdampfung bei 20 °C vernachlässigbar; eine gesundheitsschädliche Partikelkonzentration in der Luft kann jedoch beim Versprühen oder Dispergieren schnell erreicht werden, besonders als Pulver.
  • WIRKUNGEN BEI KURZZEITEXPOSITION WIRKUNGEN BEI KURZZEITEXPOSITION:
    Möglich sind Auswirkungen auf das Nervensystem mit nachfolgenden Krämpfen und Atemdepression. Cholinesterasehemmer. Die Auswirkungen treten u.U. verzögert ein. Exposition kann zum Tod führen. ärztliche Beobachtung notwendig.
  • WIRKUNGEN NACH WIEDERHOLTER ODER LANGZEITEXPOSITION Cholinesterasehemmer. Kumulative Effekte möglich (s. AKUTE GEFAHREN/SYMPTOME).
  • LECKAGE Verschüttetes Material in Behältern sammeln; falls erforderlich durch Anfeuchten Staubentwicklung verhindern. Reste sorgfältig sammeln. An sicheren Ort bringen. NICHT in die Umwelt gelangen lassen. Persönliche Schutzausrüstung: Umgebungsluftunabhängiges Atemschutzgerät.
  • R-Sätze Betriebsanweisung: R26/28:Sehr giftig beim Einatmen und Verschlucken.
    R50/53:Sehr giftig für Wasserorganismen, kann in Gewässern längerfristig schädliche Wirkungen haben.
  • S-Sätze Betriebsanweisung: S36/37:Bei der Arbeit geeignete Schutzhandschuhe und Schutzkleidung tragen.
    S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
    S60:Dieses Produkt und sein Behälter sind als gefährlicher Abfall zu entsorgen.
    S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
    S1/2:Unter Verschluss und für Kinder unzugänglich aufbewahren.
  • Chemische Eigenschaften White Solid
  • Chemische Eigenschaften Carbofuran is a broad-spectrum carbamate insecticide and nematicide. It is an odorless, white crystalline solid. On heating, it breaks down and can release toxic fumes, and irritating or poisonous gases. It is sparingly soluble in water, but very soluble in acetone, acetonitrile, benzene, and cyclohexone. The liquid formulations of carbofuran are classifi ed as RUPs because of their acute oral and inhalation toxicity to humans. Granular formulations are also classifi ed as an RUP. In fact, carbofuran was fi rst registered in the United States in 1969 and classifi ed as an RUP. Exposure to heat breaks down carbofuran, with the release of toxic fumes. Carbofuran is used for the control of soil-dwelling and foliar-feeding insects. It is also used for the control of aphids, thrips, and nematodes that attack vegetables, ornamental plants, crops of sunfl ower, potatoes, peanuts, soybeans, sugar cane, cotton, rice, and a variety of other crops
  • Chemische Eigenschaften Carbofuran is white, odorless crystalline solid.
  • Verwenden Broad-spectrum, systemic insecticide, nematocide and acaricide applied in soil to control soil insects and nematodes or on foliage to control insects and mites.
  • Verwenden Cholinesterase inhibitor. Use as systemic insecticide, acaricide, nematocide.
  • Verwenden Carbofuran is used to control soil-dwelling insect pests and nematodes in a wide range of crops.
  • Verwenden Systemic insecticide, acaricide, nematocide.
  • Allgemeine Beschreibung Carbofuran is an odorless white crystalline solid. Contact with skin may burn skin and eyes. When exposed to heat or flames Carbofuran may emit toxic oxides of nitrogen. Carbofuran is toxic by inhalation, skin contact, and/ or ingestion. Carbofuran is used as a pesticide.
  • Air & Water Reaktionen Slightly soluble in water.
  • Reaktivität anzeigen Carbofuran is a carbamate ester. Carbamates are chemically similar to, but more reactive than amides. Like amides they form polymers such as polyurethane resins. Carbamates are incompatible with strong acids and bases, and especially incompatible with strong reducing agents such as hydrides. Flammable gaseous hydrogen is produced by the combination of active metals or nitrides with carbamates. Strongly oxidizing acids, peroxides, and hydroperoxides are incompatible with carbamates. Carbofuran is unstable in an alkaline media. .
  • Health Hazard Carbofuran is extremely poisonous. May be fatal if swallowed, inhaled, or absorbed through skin. Contact may burn skin or eyes. Probable lethal oral dose to humans 5 to 50 mg/kg or 7 drops to 1 teaspoon for 150 lb. person.
  • Health Hazard Extremely toxic carbamate pesticide; routesof entry — ingestion, skin absorption, andinhalation of vapors; although the vaporpressure is very low [0.00002 torr at 33°C(91.4°F)], because of high toxicity, eventrace inhalation could be harmful; can causedeath if swallowed, absorbed through skinor inhaled; ingestion of about 0.5- to 2-gsubstance could cause death to humans; manifests acute, delayed, and chronic toxicity;choline sterase inhibitor; acute exposure maycause increased salivation, lacrimation, spontaneous urination, blurred vision, tremor,confusion, muscle twitching, and convulsion;high exposure may result in coma or respiratory collapse; other effects may includegastrointestinal effects, such as nausea, vomiting, abdominal pain, and diarrhea; cancause burn on skin contact; produced adversereproductive effects in experimental animals.
    LD50 inhalation (guinea pig): 0.043 mg/L/4 hr(RTECS 1985 )
    LD50 oral (rat): ~10 mg/kg
    LD50 rat (skin): 120 mg/kg
    Carbofuran hydrolyzes to less toxic 3-hydroxy carbamate and phenolic products.
  • Health Hazard The acute oral LD50 of carbofuran to male and female rats is about 8 mg/kg, while the acute dermal LD50 for rats is more than 3000 mg/kg. Carbofuran is mildly irritating to the eyes and skin of rabbits. The acute inhalation toxicity (LC50, 4 h) is 0.075 mg/L for rats. As with other carbamate compounds, carbofuran’s cholinesterase-inhibiting effect is short term and reversible. The symptoms of carbofuran poisoning include, but are not limited to, nausea, vomiting, abdominal cramps, sweating, diarrhea, excessive salivation, weakness, imbalance, blurring of vision, breathing diffi culty, increased blood pressure, and incontinence. Death may result at high doses from respiratory system failure associated with carbofuran exposure. Complete recovery from an acute poisoning by carbofuran, with no long-term health effects, is possible if exposure ceases and the victim has time to regain his or her normal level of cholinesterase and to recover from symptoms. Reports have indicated that risks from exposure to carbofuran are especially high among occupational workers and general public suffering with asthma, diabetes, cardiovascular disease, gastrointestinal or urogenital tracts disturbances. The available studies indicate carbofuran is unlikely to cause reproductive effects in humans at expected exposure levels. Studies indicate carbofuran is not teratogenic. No signifi cant teratogenic effects have been found in the offspring of rats given carbofuran (3 mg/kg/day) on days 5 to 19 of gestation
  • Brandgefahr May release nitrogen oxides. Containers may explode in heat of fire. Avoid alkalies. Stable under neutral or acid conditions.
  • Landwirtschaftliche Anwendung Insecticide, Acaricide, Nematicide: Carbofuran is a broad-spectrum carbamate pesticide that kills insects, mites, and nematodes on contact or after ingestion. It is used against soil and foliar pests of field, fruit, vegetable, and forest crops. Carbofuran, granule form, is banned in the U.S. A U.S. EPA restricted Use Pesticide (RUP). Not approved for use in EU countries. There are 40 global suppliers.. According to the Ecological Incident Investigation System, carbofuran has been responsible for more avian deaths than any other pesticide.
  • Handelsname A13-27164®; AU'ULTRAMICIN®; BAY 704143®; BAY 78537®; BRIFUR®; CARBODAN®; CARBOSIP 5G®; CRISFURAN®; CURETERR®; CHINUFUR®; D 1221®; DIAFURAN®; FMC 10242®; FURACARB®; FURADAN®; FURAN®; FURODAN®; KENFURAN®; KENOFURAN®; NEX®; NIA10242; NIAGARA 10242; NIAGARA NIA-10242; PILLARFURAN®; RAMPART®; YALTOX®
  • Kontakt-Allergie It is a pesticide with insecticide properties, of the carbamate group. It was implicated as a sensitizer in two farmers
  • Sicherheitsprofil to decomposition it emits toxic fumes of
  • mögliche Exposition A potential danger to those involved in the manufacture, formulation, and application of this insecticide, acaricide, and nematocide.
  • Environmental Fate Biological. Carbofuran or their metabolites (3-hydroxycarbofuran and 3-ketocarbofuran) at normal and ten times the field application rate had no effect on Rhizobium sp. However, in a nitrogen-free culture medium, Azotobacter chroococcum growth was inhibited by carbofuran, 3-hydroxycarbofuran and 3-ketocarbofuran (Kale et al., 1989). Under in vitro conditions, 15 of 20 soil fungi degraded carbofuran to one or more of the following compounds: 3-hydroxycarbofuran, 3-ketocarbofuran, carbofuran phenol and 3-hydroxyphenol (Arunachalam and Lakshmanan, 1988).
    Plant. Carbofuran is rapidly metabolized in plants to nontoxic products (Cremlyn, 1991). Metcalf et al. (1968) reported that carbofuran undergoes hydroxylation and hydrolysis in plants, insects and mice. Hydroxylation of the benzylic carbon gives 3-hydroxycarbofuran which is subsequently oxidized to 3-ketocarbofuran. In carrots, carbofuran initially degraded to 3-hydroxycarbofuran. This compound reacted with naturally occurring angelic acid in carrots forming a conjugated metabolite identified as 2,3-dihydro-2,2-dimethyl-7-(((methylamino)-carbonyl)oxy)-3-benzofuranyl (Z)-2-methyl-2-butenoic acid (Sonobe et al., 1981). Metabolites identified in three types of strawberries (Day-Neutral, Tioga and Tufts) were 2,3-dihydro-2,2-dimethyl-3-hydroxy-7-benzofuranyl-N-methylcarbamate, 2,3-dihydro-2,2-dimethyl-3-oxo-7-benzofuranyl-N-methylcarbamate, 2,3-dihydro-2,2-dimethyl-3-benzofuranol, 2,3-dihydro-2,2-dimethyl-3,7-benzofuranol and 2,3- dihydro-2,2-dimethyl-3-oxo-7-benzofuranol (Archer et al., 1977). Oat plants were grown in two soils treated with [14C]carbofuran. Most of the residues recovered in oat leaves were in the form of carbofuran and 3-hydroxycarbofuran. Other metabolites identified were 3-ketocarbofuran, a 3-keto-7-phenol and a 3-hydroxy-7-phenol (Fuhremann and Lichtenstein, 1980).
    Surface Water. Sharom et al. (1980) reported that the half-lives for carbofuran in sterilized and non-sterilized water collected from the Holly Marsh in Ontario, Canada were 2.5 to 3 weeks at pH values of 7.8–8.0 and 8.0, respectively. The half-lives observed in distilled water were 2 and 3.8 weeks at pH values of 7.0–7.2 and 6.8, respectively. They reported that chemical degradation of dissolved carbofuran was more significant than microbial degradation.
    Chemical/Physical. Releases toxic nitrogen oxides when heated to decomposition (Sax and Lewis, 1987; Lewis, 1990).
    The hydrolysis half-lives for carbofuran in a sterile 1% ethanol/water solution at 25°C and pH values of 4.5, 5.0, 6.0, 7.0 and 8.0 were 170, 690, 690, 8.2 and 1.0 week, respectively (Chapman and Cole, 1982).
  • Stoffwechselwegen The fate of carbofuran has been investigated in soils, plants, mammals, birds, fish and insects. Metabolic pathways include hydrolysis, oxidation (ring and N-methyl hydroxylation) and conjugation. The metabolism of carbofuran has been extensively reviewed by Schlagbauer and Schlagbauer (1972) and Kuhr and Dorough (1976). Metabolism in economic animals was reviewed by Akhtar (1985). Consequently the many primary publications are not usually cited.
  • Lager Carbofuran should be stored in a cool, dry, well-ventilated place, in their original containers only. It should not be kept stored or used near heat, open flame, or hot surfaces
  • Versand/Shipping UN2757 Carbamate pesticides, solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials. UN 2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name RequiredUN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required
  • Degradation Carbofuran (1) is very stable in weakly acidic media and has a DT50 of <1 year at pH 4 (22°C). It is stable in neutral media but unstable in basic conditions (PM). Carbofuran was hydrolysed to the phenol (5) with a half-life of 67 minutes at 37.5 °C at pH 9.5. 3-Ketocarbofuran (3) and N-hydroxymethylcarbofuran (4) (Scheme 2) were hydrolysed faster than carbofuran in alkaline solution (Metcalf et al., 1968). Unlabelled carbofuran was dissolved in water and irradiated by sunlight in India for 30 days. Samples were extracted and analysed by GC and TLC.
    Products were 3-ketocarbofuran (3) and the 4-hydroxycarbofuran phenol (8). (Raha and Das, 1990). Solid carbofuran was applied to glass plates and irradiated with fluorescent light or sunlight. 3-Hydroxycarbofuran (2) was detected after 2 days; 3-ketocarbofuran (3) was not detected (Metcalf et al., 1968). These pathways are illustrated in Scheme 1.
  • Inkompatibilitäten Alkaline substances, acid, strong oxidizers, such as perchlorates, peroxides, chlorates, nitrates, permanganates.
  • Waste disposal Alkaline hydrolysis is the recommended mode of disposal. In accordance with 40CFR165, follow recommendations for the disposal of pesticides and pesticide containers. Must be disposed properly by following package label directions or by contacting your local or federal environmental control agency, or by contacting your regional EPA office.
  • Vorsichtsmaßnahmen During use/handling of carbofuran, workers should wear coveralls or a long-sleeved uniform, head covering, and chemical protective gloves made of materials such as rubber, neoprene, or nitrile. Occupational workers should know that areas treated with carbofuran are hazardous. The runoff of carbofuran material and the fi re control releases irritating or poisonous gases. It is advisable that workers should enter storehouses or carbofuran-treated close spaces with caution
Carbofuran Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Carbofuran (ISO) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.
Global(0)Suppliers
1563-66-2, Carbofuran Verwandte Suche:
  • furadang
  • Furodan
  • Karbofuranu
  • Me f248
  • mef248
  • Methyl carbamic acid 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester
  • methylcarbamicacid2,3-dihydro-2,2-dimethyl-7-benzofuranylester
  • NA 2757
  • Nex
  • NIA 10242
  • nia10242
  • nia1024275wp
  • Niagara 10242
  • Niagara nia-10242
  • niagara10242
  • AGROFURAN
  • 4-DIMETHYL-AMINO-3,5-XYLYL-METHYLCARBAMATE
  • 2,3-DIHYDRO-2,2-DIMETHYL-BENZOFURAN-7-YL METHYLCARBAMATE
  • 2,3-Dihydro-2,2-dimethyl-7-benzofuranol methylcarbamate
  • 2,3-DIHYDRO-2,2-DIMETHYL-7-BENZOFURANOL N-METHYLCARBAMATE
  • 2,2-dimethyl-2,3-dihydrobenzofuranyl 7-methylcarbamate
  • 2,2-Dimethyl-2,2-dihydrobenzofuranyl-7-N-methylcarbamate
  • methylcarbamic acid 2,2-dimethyl-2,3-dihydro-7-benzofuranyl ester
  • BURAON
  • CARBOSIP
  • CARBOFURAN
  • CARBODAN
  • Bay 70143
  • CHINUFUR
  • CEKUFURAN
  • CURATERR
  • crisfuran
  • Kenofuran
  • FURADAN
  • FURADAN(R)
  • Furacarb
  • fmc 10242
  • Diafuran
  • CARBOFURAN, 1GM, NEAT
  • CARBOFURAN PESTANAL 250 MG
  • METHYLCARBAMIC ACID,3-DIHYDRO-2,2-DIMETHYL-7-BENZOFURANYL ESTER
  • Carbofuransolution,100ppm
  • Pillarfuran
  • yalox
  • Yaltox
  • 2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-yl methylcarbamate
  • 2,2-Dimethyl-2,3-dihydro-7-benzofuranyl N-methylcarbamate
  • 2,2-dimethyl-2,3-dihydro-7-benzofuranyl-n-methylcarbamate
  • 2,2-dimethyl-2,3-dihydro-7-benzofuranyln-methylcarbamate
  • 2,2-Dimethyl-2,3-dihydrobenzoduranyl-7-N-methylcarbamate
  • 2,2-Dimethyl-7-Coumaranyl N-methylcarbamate
  • 2,2-dimethyl-7-coumaranyln-methylcarbamate
  • 2,3-Dihydro-2,2-dimethyl-7-benzofuranolemethylcarbamate
  • 2,2-dimethyl-2,3-dihydrobenzofuran-7-yl methylcarbamate
  • Carbofuran Solution, 1000ppm
  • Cavbofuran
  • carbofuran (bsi,iso,ansi,esa)
  • CARBOFURAN75DB