Colestipol hydrochloride

Gefahreninformationscode (GHS)

• Bildanzeige (GHS)

  

• Alarmwort

  Warnung

• Gefahrenhinweise

  H315：Verursacht Hautreizungen.

  H319：Verursacht schwere Augenreizung.

  H335：Kann die Atemwege reizen.

• Sicherheit

  P305+P351+P338：BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.

Colestipol hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

• Verwenden

  Antihyperlipidemic.

• Verwenden

  Colestipol Hydrochloride was useful for studying pharmacokinetics with Teriflunomide (A771726).

• Definition

  ChEBI: The hydrochloride of colestipol, a highly cross-linked, high molecular weight copolymer of diethylenetriamine and epichlorohydrin (hydrochloride), with approximately 1 out of 5 amine nitrogens protonated. It is used for binding bile acids in the intestine, inhibiting their reabsorption.

• Trademarks

  Colestid (Pharmacia & Upjohn).

• Allgemeine Beschreibung

  Colestipol (Colestid) is ahigh–molecular-weight, insoluble, granular copolymer oftetraethylenepentamine and epichlorohydrin. It functions asan anion-exchange, resin-sequestering agent in a manner similarto that of cholestyramine resin. Colestipol hydrochloridereduces cholesterol levels without affecting triglycerides andseems to be especially effective in the treatment of type IIhyperlipoproteinemias.

• Arzneimittelwechselwirkung

  Potentially hazardous interactions with other drugs
  Anticoagulants: may enhance or reduce effects of coumarins and phenindione.
  Ciclosporin: no reports of an interaction; however, ciclosporin levels should be carefully monitored if colestipol and ciclosporin are prescribed concurrently, as colestipol may interfere with ciclosporin absorption.

• Stoffwechsel

  Not applicable as colestipol is not systemically absorbed.

Colestipol hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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