Benzothiazol-2-thiol

Bezeichnung:Benzothiazol-2-thiol

CAS-Nr149-30-4

Englisch Name:2-Mercaptobenzothiazole

CBNumberCB2853123

SummenformelC7H5NS2

Molgewicht167.25

MOL-Datei149-30-4.mol

Synonyma

Benzothiazol-2-thiol

Benzothiazolthiol

Benzothiazol-2-thion

Benzothiazol-2-thiol physikalisch-chemischer Eigenschaften

Schmelzpunkt	177-181 °C(lit.)
Siedepunkt	223°C (rough estimate)
chüttdichte	390kg/m3
Dichte	1.42
Dampfdruck	<0.000003 hPa (25 °C)
Brechungsindex	1.6100 (estimate)
Flammpunkt	243 °C
storage temp.	Store below +30°C.
Löslichkeit	0.12g/l
Aggregatzustand	Powder
pka	9.80±0.20(Predicted)
Farbe	Yellow
Geruch (Odor)	Odorless
PH	7 (0.12g/l, H2O, 25℃)
Explosionsgrenze	15%(V)
Wasserlöslichkeit	<0.1 g/100 mL at 19 ºC
maximale Wellenlänge (λmax)	325nm(MeOH)(lit.)
Sensitive	Air Sensitive
Merck	14,5868
BRN	119484
Henry's Law Constant	2.7×10² mol/(m³Pa) at 25℃, HSDB (2015)
Stabilität	Stable. Incompatible with strong oxidizing agents. Flammable.
InChI	1S/C7H5NS2/c9-7-8-5-3-1-2-4-6(5)10-7/h1-4H,(H,8,9)
InChIKey	YXIWHUQXZSMYRE-UHFFFAOYSA-N
SMILES	Sc1nc2ccccc2s1
LogP	2.86
CAS Datenbank	149-30-4(CAS DataBase Reference)
IARC	2A (Vol. 115) 2018
NIST chemische Informationen	2-Mercaptobenzothiazole(149-30-4)
EPA chemische Informationen	2-Mercaptobenzothiazole (149-30-4)

Sicherheit

Kennzeichnung gefährlicher	Xi,N
R-Sätze:	43-50/53
S-Sätze:	24-37-60-61
RIDADR	UN 3077 9/PG 3
WGK Germany	2
RTECS-Nr.	DL6475000
F	9-13-23
Selbstentzündungstemperatur	465 °C
TSCA	TSCA listed
HazardClass	9
PackingGroup	III
HS Code	29342020
Speicherklasse	11 - Combustible Solids
Hazard Classifications	Aquatic Acute 1 Aquatic Chronic 1 Skin Sens. 1
Giftige Stoffe Daten	149-30-4(Hazardous Substances Data)
Toxizität	LD50 orally in Rabbit: 1680 mg/kg LD50 dermal Rabbit > 7940 mg/kg

Gefahreninformationscode (GHS)

2-Mercaptobenzothiazole Chemische Eigenschaften,Einsatz,Produktion Methoden

ERSCHEINUNGSBILD
GELBE KRISTALLE MIT STECHENDEM GERUCH.
CHEMISCHE GEFAHREN
Zersetzung beim Verbrennen unter Bildung giftiger und reizender Rauche (Schwefeloxide, Stickstoffoxide). Reagiert mit Säuren oder Säurerauchen unter Bildung giftiger Rauche (Stickstoffoxide, Schwefeloxide).
ARBEITSPLATZGRENZWERTE
TLV nicht festgelegt (ACGIH 2005).
MAK: 4 mg/m?(Einatembare Fraktion); Sensibilisierung der Haut; Krebserzeugend Kategorie 3B; Schwangerschaft: Gruppe C; (DFG 2005).
INHALATIONSGEFAHREN
Verdampfung bei 20°C vernachlässigbar; eine gesundheitsschädliche Partikelkonzentration in der Luft kann jedoch beim
WIRKUNGEN BEI KURZZEITEXPOSITION
WIRKUNGEN BEI KURZZEITEXPOSITION:
Die Substanz reizt die Augen.
WIRKUNGEN NACH WIEDERHOLTER ODER LANGZEITEXPOSITION
Wiederholter oder andauernder Kontakt kann zu Hautsensibilisierung führen.
LECKAGE
Verschüttetes Material in abdichtbaren Behältern sammeln; falls erforderlich durch Anfeuchten Staubentwicklung verhindern. Reste sorgfältig sammeln. An sicheren Ort bringen. NICHT in die Umwelt gelangen lassen. Persönliche Schutzausrüstung: Atemschutzgerät, P2-Filter für schädliche Partikel.
R-Sätze Betriebsanweisung:
R43:Sensibilisierung durch Hautkontakt möglich.
R50/53:Sehr giftig für Wasserorganismen, kann in Gewässern längerfristig schädliche Wirkungen haben.
S-Sätze Betriebsanweisung:
S24:Berührung mit der Haut vermeiden.
S37:Geeignete Schutzhandschuhe tragen.
S60:Dieses Produkt und sein Behälter sind als gefährlicher Abfall zu entsorgen.
S61:Freisetzung in die Umwelt vermeiden. Besondere Anweisungen einholen/Sicherheitsdatenblatt zu Rate ziehen.
Beschreibung
Mercaptobenzothiazole is a rubber chemical, an accelerant of vulcanization. It is contained in the "mercapto mix". The most frequent occupational categories are metal industry, homemakers, health services and laboratories, building industries, and shoemakers. It is also used as a corrosion inhibitor in cutting fluids or in releasing fluids used in the pottery industry.
Chemische Eigenschaften
pale yellow monoclinic needle-like or flaky crystals with a disagreeable odor. Insoluble in water and gasoline, soluble in ethanol, ethyl ether, acetone, ethyl acetate, benzene, chloroform and dilute alkali solution.
Verwenden
2-Mercaptobenzothiazole (MBT) is an industrial chemical that is used principally in the manufacture of rubber.Vulcanization accelerator for type of rubber usually used in the production of household rubber gloves rather than medical rubber gloves; corrosion inhibitor in metal-working fluids, detergents, antifreeze, and photographic emulsions. In addition, 2-MBT is formed as a reaction product from some vulcanisation accelerators in elastomer production.
Application
2-mercaptobenzothiazole is an accelerator, retarder, and peptizer for natural and other rubber products, but is also used as a corrosion inhibitor in soluble cutting oils and antifreeze mixtures; in greases, adhesives, photographic-film emulsions; detergents; veterinary products, such as tick and flea powders and sprays.It is added to polyether polymers as a stabilizer to resist damage by air and ozone, and is a component approved in the USA in some skin medications for dogs (HSDB, 2015).
2-Mercaptobenzothiazole is also used as an intermediate in the production of pesticides such as 2-(thiocyanomethylthio)benzothiazole (Azam & Suresh, 2012), and sodium and zinc salts of 2-mercaptobenzothiazole are approved for use as pesticides by the EPA (1994).
synthetische
2-Mercaptobenzothiazole is produced by reacting aniline, carbon disulfide, and sulfur at high temperature and pressure; the product is then purified by dissolution in a base to remove the dissolved organics. Re-precipitation is achieved by the addition of acid (Kirk-Othmer, 1982; NTP, 1988).
Refined 2-mercaptobenzothiazole was produced by recrystallization from 2-mercaptobenzothiazole with industrial grade and oxidized to 2,2'-dithiobis(benzothiazole), using oxygen as an oxidant, nitric oxide as a oxygen carrier and alcohols as solvents, in a circulating fluidized reactor under one-step oxidation. 2,2'-Dithiobis(benzothiazole) was thus obtained with high purity up to 99 %, melting point at 183 oC, high yield over 98 %, through the optimization of reaction parameters as reaction time, temperature, reactants ratio, with less waste generation and emission during the production process. Alcohol solvents can be reused after purification.
http://dx.doi.org/10.14233/ajchem.2013.14030
Definition
ChEBI: 2-Mercaptobenzothiazole is a 1,3-Benzothiazole substituted at the 2-position with a sulfanyl group. It is used as a vulcanisation accelerator in the crosslinking of rubber.
Synthesis Reference(s)
The Journal of Organic Chemistry, 26, p. 3436, 1961 DOI: 10.1021/jo01067a101
Allgemeine Beschreibung
Pale yellow to tan crystalline powder with a disagreeable odor.
Air & Water Reaktionen
Insoluble in water.
Reaktivität anzeigen
2-Mercaptobenzothiazole is incompatible with strong oxidizing agents. Also incompatible with acids and acid fumes.
Health Hazard
Thiazoles cause allergic skin reactions of type IV [delayed-type hypersensitivity (DTH)].
2-mercaptobenzothiazole is a Standardized Chemical Allergen. The physiologic effect of 2-mercaptobenzothiazole is by means of Increased Histamine Release, and Cell-mediated Immunity.
Brandgefahr
2-Mercaptobenzothiazole is combustible.
Sicherheitsprofil
Suspected carcinogen withexperimental carcinogenic and tumorigenic data. Poisonby ingestion and intraperitoneal routes. Experimentalteratogenic and reproductive effects. Mutation datareported. Incompatible with oxidizers. When heated todecomposition
Toxikologie
2-Mercaptobenzothiazole has a sensitizing effect, and with chronic exposure (e.g., through the use of rubber gloves) it may induce skin reactions. 2-Mercapto-1-methylimidazole displays teratogenic effects in humans, and it is suspected of being a carcinogen. 6-Mercaptopurine derivatives influence cell division, and have been employed as cytostatic agents. They have been found to be teratogenic in animal studies. Methylthio-substituted triazines, which are used as herbicides, are only slightly toxic. The corresponding LD50 or LC50 values derived from animal studies are above the level of 1000 mg/ kg. Similar values have been established for a methylthiotriazinone that is the active ingredient in the herbicide Sencor.
Carcinogenicity
MBT was not mutagenic in Ames bacterial assays, but it induced chromosomal damage in mammalian cells in culture. Reproductive effects were not observed in two-generation studies of rats treated with up to 15,000 ppm MBT in the diet.
läuterung methode
Crystallise it repeatedly from 95% EtOH, or purify it by incomplete precipitation by dilute H2SO4 from a basic solution, followed by several crystallisations from acetone/H2O or *benzene. It complexes with Ag, Au, Bi, Cd, Hg, Ir, Pt, and Tl. [Beilstein 27 II 233, 27 III/IV 2709.]
Filter für giftige stoffe
The initial risk screening level (IRSL) for 2-mercaptobenzothiazole (CAS # 149-30-4) is 0.54 μg/m3 annual averaging time and the secondary risk screening level (SRSL) is 5.4 μg/m3 annual averaging time.

2-Mercaptobenzothiazole Upstream-Materialien And Downstream Produkte

Benzothiazol-2-thiol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

149-30-4, 2-Mercaptobenzothiazole Verwandte Suche:

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