Sulisobenzon

Bezeichnung:Sulisobenzon

CAS-Nr4065-45-6

Englisch Name:2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid

CBNumberCB1359279

SummenformelC14H12O6S

Molgewicht308.31

MOL-Datei4065-45-6.mol

Synonyma

Sulisobenzon

Sulisobenzon physikalisch-chemischer Eigenschaften

Schmelzpunkt	170 °C
Siedepunkt	0°C
Dichte	1.4574 (rough estimate)
Dampfdruck	0Pa at 25℃
Brechungsindex	1.5300 (estimate)
Flammpunkt	0°C
storage temp.	Inert atmosphere,Room Temperature
Löslichkeit	DMSO (Slightly), Methanol (Slightly)
pka	-0.70±0.50(Predicted)
Farbe	White to Off-White
Wasserlöslichkeit	300.92g/L at 25℃
Merck	14,8983
BRN	2889165
InChIKey	CXVGEDCSTKKODG-UHFFFAOYSA-N
LogP	0.515 at 25℃
CAS Datenbank	4065-45-6(CAS DataBase Reference)
EPA chemische Informationen	Sulisobenzone (4065-45-6)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38
S-Sätze:	26-36-37/39-36/37/39-27
WGK Germany	1
RTECS-Nr.	DB5044300
TSCA	Yes
HS Code	29147000
Giftige Stoffe Daten	4065-45-6(Hazardous Substances Data)

Gefahreninformationscode (GHS)

2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S36/37/39:Bei der Arbeit geeignete Schutzkleidung,Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S27:Beschmutzte, getränkte Kleidung sofort ausziehen.
Chemische Eigenschaften
white to yellowish powder
Originator
Uval,Dome,US,1965
Verwenden
sulisobenzone is the drug name for benzophenone-4, a sunscreen chemical.
Verwenden
Ultraviolet absorber for leather and textile fibers; in cosmetics and shampoos.
Verwenden
ultraviolet screen
Verwenden
2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid is a commonly used, FDA approved sunscreen chemical with uVA-absorbing properties and an approved usage level of 5 to 10 percent. It protects a formulation from the effects of uV-light exposure.
Definition
ChEBI: Sulisobenzone is a member of benzophenones.
Manufacturing Process
663 g of dichloroethane and 74.6 g 2-hydroxy-4-methoxybenzophenone were charged into a 3-neck flask equipped with stirrer, thermometer, reflux condenser and dropping funnel and a heating mantle. The solution was heated to the reflux temperature (85°C to 86°C) and was dehydrated by distilling off 66.5 g 1,2-dichloroethane. While maintaining at reflux, 30 g chlorosulfonic acid was added slowly over a period of about two hours. The rate of addition was regulated by the speed of evolution of the HCl. After all the chlorosulfonic acid was added, the charge was still maintained at reflux for an additional 15 minutes to remove traces of HCl. It was then cooled to 5°C and filtered. The filter cake was washed with 500 g cold 1,2-dichloroethane and dried. 98 g of product were obtained.
Trademarks
Sungard (Bayer).
Therapeutic Function
Sunscreen agent
Allgemeine Beschreibung
Sulisobenzone is a broad spectrum organic UV filter in sunscreen formulations, known to absorb deleterious UV light.
Flammability and Explosibility
Non flammable
Kontakt-Allergie
BZP-4 is widely used in cosmetics, particularly shampoos and hair products. Cross-reactivity is rarely expected in patients photoallergic to ketoprofen.

2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid Upstream-Materialien And Downstream Produkte

Sulisobenzon Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

4065-45-6, 2-Hydroxy-4-methoxybenzophenone-5-sulfonic acid Verwandte Suche:

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