2-(2H-Benzotriazol-2-yl)-p-kresol

Bezeichnung:2-(2H-Benzotriazol-2-yl)-p-kresol

CAS-Nr2440-22-4

Englisch Name:Drometrizole

CBNumberCB6426334

SummenformelC13H11N3O

Molgewicht225.25

MOL-Datei2440-22-4.mol

Synonyma

2-(2H-Benzotriazol-2-yl)-p-kresol

2-(2H-Benzotriazol-2-yl)-p-kresol physikalisch-chemischer Eigenschaften

Schmelzpunkt	125.5-129.5 °C(lit.)
Siedepunkt	bp10 225°
Dichte	1.38
Dampfdruck	0Pa at 20℃
Brechungsindex	1.5600 (estimate)
Flammpunkt	54°C
storage temp.	15-25°C
Löslichkeit	DMSO (Slightly), Methanol (Slightly)
Aggregatzustand	Solid
pka	8.15±0.43(Predicted)
Farbe	Off-White to Pale Yellow
Wasserlöslichkeit	173μg/L at 20℃
Merck	14,3447
Stabilität	Hygroscopic
InChIKey	MCPKSFINULVDNX-UHFFFAOYSA-N
LogP	4.2 at 25℃
CAS Datenbank	2440-22-4(CAS DataBase Reference)
NIST chemische Informationen	Phenol, 2-(2H-benzotriazol-2-yl)-4-methyl-(2440-22-4)
EPA chemische Informationen	2-(2H-Benzotriazol-2-yl)-p-cresol (2440-22-4)

Sicherheit

Kennzeichnung gefährlicher	Xi
R-Sätze:	36/37/38-53-43
S-Sätze:	22-24/25-36/37
WGK Germany	1
RTECS-Nr.	GO6860000
HS Code	29339900
Toxizität	LD50 oral in mouse: 6500mg/kg

Gefahreninformationscode (GHS)

Drometrizole Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Chemische Eigenschaften
Light yellow powder
Verwenden
Drometrizole is an intermediate reactant in the synthesis of UV light absorbers for polyester fibers.
Verwenden
2(2-Hydroxy-5-methylphenyl)benzotriazol is an UV adsorber for use in plastics, cosmetics, dental materials, acrylic materials, dyes, etc.
Verwenden
An ultraviolet light absorber for stabilizing plastics and other organic materials against discoloration and deterioration.
Application
Intermediate reactant in the synthesis of UV light absorbers for polyester fibers
Reactant for synthesis of:
Benzotriazole UV absorbers with a blocked hydroxy group for us in UV curable paint
Maleimide-bound benzotriazole monomer to use for emulsion polymerization
Used in:
Microstereophotolithography and shape memory alloy for fabrication of miniaturized actuators
PVS and wood / PVC composites as a stabilizer
Acrylonitrile-butadiene-styrene as a UV absorber.
Definition
Drometrizole is a member of triazoles.
Flammability and Explosibility
Not classified
Toxicity evaluation
The mutagenicity study of drometrizole was performed using Salmonella typhimurium strains TA1538 and TA98 with metabolic activation in the Ames’ test. Spot test (10 and 100 mg drometrizole/plate) and top agar method (50 and 100 mg drometrizole/plate) were conducted. The results showed that drometrizole was not mutagenic.Mice and rats were administered 5.0 or 10.0 g/kg of drometrizole in sunflower oil by stomach tube intubation. After body weight and behaviour were monitored for 3 weeks, acute toxicity of drometrizole was evaluated to be low. The oral lethal dose (LD50) of drometrizole in mice was reported to be 6.5 g/kg and > 5.0g/kg. Oral toxicity was evaluated in rats for nail care cosmetics containing 1%, 0.3% and 0.03% of drometrizole. The LD50 of products containing 1% of drometrizole was > 15.0 g/kg. The LD50 of products containing 0.3% and 0.03% drometrizole was > 5.0 g/kg. No acute toxicity was observed in these treatments.

Drometrizole Upstream-Materialien And Downstream Produkte

2-(2H-Benzotriazol-2-yl)-p-kresol Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

2440-22-4, Drometrizole Verwandte Suche:

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