Dinatrium-3,3'-[[1,1'-biphenyl]-4,4'-diylbis(azo)]bis(4-aminonaphthalin-1-sulfonat)

Bezeichnung:Dinatrium-3,3'-[[1,1'-biphenyl]-4,4'-diylbis(azo)]bis(4-aminonaphthalin-1-sulfonat)

CAS-Nr573-58-0

Englisch Name:Congo Red

CBNumberCB1261000

SummenformelC32H22N6Na2O6S2

Molgewicht696.66

MOL-Datei573-58-0.mol

Synonyma

Dinatrium-3,3'-[[1,1'-biphenyl]-4,4'-diylbis(azo)]bis(4-aminonaphthalin-1-sulfonat)

Dinatrium-3,3'-[[1,1'-biphenyl]-4,4'-diylbis(azo)]bis(4-aminonaphthalin-1-sulfonat) physikalisch-chemischer Eigenschaften

Schmelzpunkt	>360 °C (lit.)
Dichte	0.995 g/mL at 25 °C
Dampfdruck	<1 Pa
storage temp.	Store at +5°C to +30°C.
Löslichkeit	H2O: soluble10mg/mL
Colour Index	22120
Aggregatzustand	Powder/Solid
pka	4.1(at 25℃)
Farbe	Red Brown
PH	6.7 (10g/l, H2O, 20℃)
Säure-Base-Indikators(pH-Indikatoren)	3(blue)-5.2(red)
Geruch (Odor)	Odorless
Wasserlöslichkeit	soluble
maximale Wellenlänge (λmax)	497nm, 488nm, 595nm
Merck	14,2498
BRN	3894858
Stabilität	Stable. Incompatible with strong oxidizing agents.
Biologische Anwendungen	Detecting bacteria,protein folding disorders; treating dermatological disorders,neurodegenerative diseases,Alzheimer’s disease
Major Application	Waveguides, optical sensors, display devices, inks, fertilizer, pesticides, carbohydrates, treatment of pathogen infections, age-related macular degeneration
CAS Datenbank	573-58-0(CAS DataBase Reference)
EPA chemische Informationen	Congo Red (573-58-0)

Sicherheit

Kennzeichnung gefährlicher	T,Xi
R-Sätze:	45-63-36
S-Sätze:	53-45-37/39-26
WGK Germany	3
RTECS-Nr.	QK1400000
TSCA	Yes
HS Code	29215900
Giftige Stoffe Daten	573-58-0(Hazardous Substances Data)
Toxizität	LD50 i.v. in rats: 190 mg/kg (Richardson, Dillon)

Gefahreninformationscode (GHS)

Congo Red Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R45:Kann Krebs erzeugen.
R63:Kann das Kind im Mutterleib möglicherweise schädigen.
R36:Reizt die Augen.
S-Sätze Betriebsanweisung:
S53:Exposition vermeiden - vor Gebrauch besondere Anweisungen einholen.
S45:Bei Unfall oder Unwohlsein sofort Arzt zuziehen (wenn möglich, dieses Etikett vorzeigen).
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Beschreibung
C.I. Direct red 28(Congo Red) is an odorless,brownish-red powder. Molecular weight =698.72. Meltingpoint =359℃. Soluble in water; solubility =25 g/L at25℃.
Chemische Eigenschaften
C.I. Direct red 28(Congo Red) is an odorless, brownish-red powder.
Chemische Eigenschaften
brown-red powder
Verwenden
Dye, medicine (diagnostic aid), indicator, biological stain.
Verwenden
Congo red is useful for staining and visual detection of amyloid deposits. It inhibits the accumulation of the scrapie-associated, protease-resistant isoform of protein PrP without affecting the metabolism of the normal isoform.
Verwenden
- Congo red has been used as a histochemical stain for the quantification of amyloid deposits in brain tissues.
- It has been used as a cell wall inhibiting agent in fungus Cryptococcus neoformans.
- It has also been used to study microstructural details in the cell walls of raw potato and fried potato using confocal microscopy.
Definition
ChEBI: An indicator dye that is blue-violet at pH 3.0 and red at pH 5.0.
Biochem/physiol Actions
Congo red is a benzidine-based anionic diazo dye. It is a histological dye which binds to many amyloid proteins and is used for the quantification of amyloid β-peptide aggregation. Congo red also interacts with β-D-glucans, polysaccharides containing continuous β-(1→4)-linked D-glucopyranosyl units and some hemicellulosic galactoglucomannans.
Sicherheitsprofil
Human poison by ingestion with cardovascular effects. Experimental poison by intravenous route. An experimental teratogen. Experimental reproductive effects. An eye irritant. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx, SOx, and Na2O
mögliche Exposition
It is used as an indicator dye, a biological stain; a diagnostic aid in medicine; and a dye for fabric and paper.
Erste Hilfe
If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. If victim is conscious, administer water ormilk. Do not induce vomiting.
Lager
Room temperature
Versand/Shipping
UN3143 Dyes, solid, toxic, n.o.s. or Dye intermediates, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required
läuterung methode
Crystallise the dye from aqueous EtOH (1:3). Dry it in air. [Beilstein 6 I 342.]

Properties and Applications

Standard	Acid Resistance	Alkali Resistance	Light Fastness	Soaping		Water
Standard	Acid Resistance	Alkali Resistance	Light Fastness	Fading	Stain	Fading	Stain
ISO	1	3	1	2		2
AATCC	1	3	2	1		3

Inkompatibilitäten
Contact with oxidizers may cause fire and explosion hazard. Incompatible with strong acids; reducing agents.

Congo Red Upstream-Materialien And Downstream Produkte

Dinatrium-3,3'-[[1,1'-biphenyl]-4,4'-diylbis(azo)]bis(4-aminonaphthalin-1-sulfonat) Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

573-58-0, Congo Red Verwandte Suche:

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