Calciumgluconat

Bezeichnung:Calciumgluconat

CAS-Nr299-28-5

Englisch Name:Calcium gluconate

CBNumberCB0473578

SummenformelC12H22CaO14

Molgewicht430.37

MOL-Datei299-28-5.mol

Synonyma

Calciumgluconat

Calciumgluconat physikalisch-chemischer Eigenschaften

Schmelzpunkt	195°C
alpha	10.2 º (c=1, H2O 22 ºC)
Siedepunkt	400℃[at 101 325 Pa]
Dichte	1.677[at 20℃]
Dampfdruck	0.004Pa at 20℃
storage temp.	Inert atmosphere,Room Temperature
Löslichkeit	Sparingly soluble in water, freely soluble in boiling water.
Aggregatzustand	Crystals or Crystalline Powder
Farbe	White
PH	pH;6.0～8.0
Geruch (Odor)	at 100.00?%. odorless
Wasserlöslichkeit	3.3 g/100mL
Hydrolytic Sensitivity	0: forms stable aqueous solutions
Merck	14,1669
Stabilität	Stable. Incompatible with strong oxidizing agents.
InChIKey	KYUVBRZSDFBLTH-OSQBQZLYSA-M
LogP	-5.31 at 20℃
CAS Datenbank	299-28-5(CAS DataBase Reference)
EPA chemische Informationen	D-Gluconic acid, calcium salt (2:1) (299-28-5)

Sicherheit

Kennzeichnung gefährlicher	Xn
R-Sätze:	20/21/22-36/37/38
S-Sätze:	24/25-36-26
WGK Germany	1
RTECS-Nr.	EW2100000
TSCA	No
HS Code	29181600
Giftige Stoffe Daten	299-28-5(Hazardous Substances Data)
Toxizität	dog,LDLo,intravenous,1987mg/kg (1987mg/kg),Journal of Pharmacology and Experimental Therapeutics. Vol. 47, Pg. 183, 1933.

Gefahreninformationscode (GHS)

Calcium gluconate Chemische Eigenschaften,Einsatz,Produktion Methoden

R-Sätze Betriebsanweisung:
R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-Sätze Betriebsanweisung:
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
Chemische Eigenschaften
white crystalline powder or granules
Verwenden
Calcium Gluconate is used as an inert ingredient in pesticide formulations applied to crops. It is also used as a supplement to fortify beverages and foods lacking a sufficient amount of calcium.
Verwenden
In sewage purification; in coffee powders to prevent caking.
Verwenden
analgesic, antipyretic
Verwenden
Calcium Gluconate is a white crystalline granule or powder that functions as a firming agent, formulation aid, sequestrant, and sta- bilizer. at room temperature the anhydrous form has a solubility of approximately 1 g in 30 ml of water, which improves in boiling water to approximately 1 g in 5 ml of water. it also exists as calcium gluconate (monohydrate). it is used as a source of calcium ions for sodium alginate gels, and as a calcium fortifier in baked goods, pud- dings, and dairy product analogs. it functions as a coagulation aid in milk and instant pudding powders and as a means of masking the bitter aftertaste of some artificial sweeteners.
Definition
ChEBI: Calcium gluconate is the calcium salt of D-gluconic acid. It has a role as a nutraceutical. It contains a D-gluconate.
Trademarks
Calglucon (Novartis).
Flammability and Explosibility
Non flammable
Industrielle Verwendung
calcium gluconate [Ca(C₆H₁₁O₇)₂] is used as a food additive in vitamin pills.injection of a 10% calcium gluconate has been recommended. It has to be kept in mind that the plasma Ca²⁺ level and any changes to the electrocardiogram (ECG) have to be carefully monitored.
Clinical Use
Hypocalcaemia
Sicherheitsprofil
Moderately toxic by subcutaneous, intraperitoneal, and intravenous routes. Human systemic effects in infants by intramuscular route: dermatitis and fever. When heated to decomposition it emits acrid smoke and fumes. See also CALCIUM COMPOUNDS.
Veterinary Drugs and Treatments
Calcium salts are used for the prevention or treatment of hypocalcemic conditions.
Arzneimittelwechselwirkung
Potentially hazardous interactions with other drugs
Can impair absorption of some drugs, e.g. iron, ciprofloxacin.
Stoffwechsel
Calcium is absorbed mainly from the small intestine by active transport and passive diffusion. About one-third of ingested calcium is absorbed although this can vary depending upon dietary factors and the state of the small intestine. 1,25-Dihydroxycholecalciferol (calcitriol), a metabolite of vitamin D, enhances the active phase of absorption. Excess calcium is mainly excreted renally. Unabsorbed calcium is eliminated in the faeces, together with that secreted in the bile and pancreatic juice. Minor amounts are lost in the sweat, skin, hair, and nails.
läuterung methode
Dissolve it in H2O, filter and precipitate it by adding MeOH. Filter off the solid and dry it in a vacuum at 85o. Alternatively, dissolve it in H2O, filter (from insoluble inorganic Ca) and evaporate it to dryness under vacuum at 85o. [March et al. J Am Pharm Assoc 41 366 1952, Beilstein 3 IV 1255.]

Calcium gluconate Upstream-Materialien And Downstream Produkte

Calciumgluconat Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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