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63223-86-9

供应商 相关产品 基本信息 理化性质 应用领域 常见问题列表 图谱信息 人参皂甙 Rh1价格(试剂级)

产品图片

基本信息

英文
Ginsenoside Rh1
中文
人参皂甙 Rh1
英文名称
GINSENOSIDE RH1
Sanchinoside B2
gensenoside Rh1
Prosapogenin A2
sanchinoside rh1
(S)Ginsenoside-Rh1
GINSENOSIDE Rh1(SH)
Ginsenoside Rh1 ,98%
Ginsenoside Rh1 (Prosapogenin A2
Ginsenoside Rh1, 98%, from Panax ginseng C. A. Mey.
CAS
63223-86-9
中文名称
人参皂荚RH1
人参皂苷-RH1
人参皂甙 Rh1
S-人参皂苷RH1
人参皂苷RH1(S)
人参皂苷 S-RH1
(R型)人参皂苷RH1
(S型)人参皂苷RH1
人参皂苷RH1(标准品)
人参皂苷RH1, 来源于人参
分子式
C35H60O9
分子量
624.85
MOL 文件
63223-86-9.mol

理化性质

外观性状
白色粉末，可溶于甲醇、乙醇、DMSO等有机溶剂，来源于人参。
沸点 
755.1±60.0 °C(Predicted)
密度 
1.23
储存条件 
Sealed in dry,2-8°C
酸度系数(pKa)
12.91±0.70(Predicted)

应用领域

用途1
(20S)-人参皂苷Rh1是人参中的主要成分之一，具有抗炎作用。

常见问题列表

理化性质
人参皂苷Rh1来源为五加科植物人参Panax ginseng C. A. Mey.的干燥根,是一种白色粉末状物质，溶解性:易溶于水、甲醇、乙醇，不溶于乙/醚、苯。
生物活性
20(S)-Ginsenoside Rh1 (Prosapogenin A2, Sanchinoside B2, Sanchinoside Rh1)是从红参中提取的主要生物活性化合物之一，在世界范围内，红参已越来越多地用于增强认知和身体健康。它具有抗发炎、抗氧化、免疫调节作用和对神经系统有积极作用的有效特性。20(S)-Ginsenoside Rh1 可抑制 PPAR-γ、TNF-α、IL-6 和 IL-1β 的表达。
靶点

PPAR-γ

TNF-α

IL-6

IL-1β

Human Endogenous Metabolite


体外研究

The effect of Ginsenoside Rh1 is examined on adipogenesis in 3T3-L1 cells. Ginsenoside Rh1 potently inhibits the adipogenesis, as assessed by Oil-red O staining and lipid contents in 3T3-L1 adipocytes. Ginsenoside Rh1, at concentrations of 50 μM and 100 μM, inhibit the adipogenesis by 50% and 63%, respectively.The expression levels of adipocytespecific genes such as PPAR-γ, C/EBP-α, FAS, aFABP and some genes are examined during early phase of differentiation such as Pref-1, C/EBP-δ and Glucocorticoid receptor (GR). After the treatment with Ginsenoside Rh1 in 3T3-L1 cells, mRNA is extracted on 18 h and 24 h for Pref-1, C/EBP-δ and GR and day 8 for PPAR-γ, C/EBP-α, FAS, aFABP. Then, the expression profiles of adipocyte-specific genes are investigated by RT-PCR. PPAR-γ, C/EBP-α, FAS, and aFABP expressions are significantly increased in DMI-stimulated differentiated adipocyte compared to those of non-stimulated adipocyte cells. However, treatment with DMI in the presence of Ginsenoside Rh1 significantly suppresses the expression levels of PPAR-γ, C/EBP-α, FAS, and aFABP in a dose- dependent manner, whereas the expression levels of Pref-1, C/EBP-δ and GR are not affected.


体内研究

When high-fat diet (HFD) fed mice for 8 weeks, body and epididymal fat weight gains are significantly increased compared to those of low-fat diet (LFD)-fed mice. However, when Ginsenoside Rh1 is treated in HFD-fed mice, body and epididymal fat weight gains are significantly decrease compared with those of the HFD-fed mice. TG, glucose, insulin, total cholesterol, and HDL levels in the blood are significantly increased in HFD-fed mice group compared to LFD-fed mice group. Treatment with Ginsenoside Rh1 in HFD-fed mice significantly lowers TG level alone.


图谱信息

图谱信息
人参皂甙 Rh1(63223-86-9)质谱(MS)

人参皂甙 Rh1价格(试剂级)

人参皂甙 Rh1价格(试剂级)
更新日期产品编号产品名称CAS号包装价格
2023/01/06XW080031人参皂苷RH1
ginsenoside rh1;(20s)-6α-(β-d-glucopyranosyloxy)-3β,12β,20-trihydroxydammara-24-ene;(20s)-6α-(β-d-glucopyranosyloxy)dammar-24-ene-3β,12β,20-triol		63223-86-920MG602元
2023/01/06S9129人参皂甙 Rh1
20(S)-Ginsenoside Rh1		63223-86-91mg1040.63元
2022/09/18HY-N0604人参皂甙 Rh1
Ginsenoside Rh1		63223-86-95mg600元

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