11021-14-0
基本信息
人参皂苷RC
GINSENOSIDE RC
20-[(6-O-alpha-L-arabinofuranosyl-beta-D-glucopyranosyl)oxy]-12beta-hydroxydammar-24-en-3beta-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
GINSENOSIDE FROM GINSENG ROOT (PANAX*QUI NQUEFOLIUM
ginsenoside-rc from panax quinquefolium (american ginseng)root
Ginsenoside Rc (CAS# 11021-14-0)
20-[(6-O-alpha-L-Arabinofuranosyl-beta-D-glucopyranosyl)oxy]-12b-hydroxydammar-24-en-3b-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
GINSENOSIDE RC WITH HPLC
arabinofuranosyl-β-D-glucopyranosyl)oxy]-12-
glucopyranosyl-
hydroxydammar-24-en-3-yl2-O-β-D-
Panaxoside Rc
[20-[(6-O-α-L-Arabinofuranosyl-β-D-glucopyranosyl)oxy]-12β-hydroxydammar-24-en-3β-yl]2-O-β-D-glucopyranosyl-β-D-glucopyranoside
3β-[2-O-(β-D-Glucopyranosyl)-β-D-glucopyranosyloxy]-20-[6-O-(α-L-arabinofuranosyl)-β-D-glucopyranosyloxy]dammara-24-ene-12β-ol
物理化学性质
| 外观性状 | 白色结晶粉末，可溶于甲醇、乙醇、DMSO等有机溶剂，来源于人参根茎。 |
| 熔点 | 199～201℃ |
| 沸点 | 1128.3±65.0 °C(Predicted) |
| 密度 | 1.42±0.1 g/cm3(Predicted) |
| 储存条件 | 2-8°C |
| 溶解度 | DMSO（微量）、甲醇（微量）、吡啶（微量） |
| 酸度系数(pKa) | 12.85±0.70(Predicted) |
| 形态 | 固体 |
| 颜色 | 白色至淡黄色 |
| 检测方法 | NMR,HPLC |
| 稳定性 | 吸湿性 |
| LogP | 5.100 (est) |
| CAS 数据库 | 11021-14-0(CAS DataBase Reference) |
安全数据
| 危险性符号(GHS) |  GHS07 |
| 警示词 | 警告 |
| 危险性描述 | H302 |
| 防范说明 | P301+P312+P330 |
| 危险品标志 | Xn |
| 危险类别码 | R20/21/22 |
| 安全说明 | S26-S36 |
| WGK Germany | 3 |
| RTECS号 | LY9536300 |
| 海关编码 | 29389090 |
知名试剂公司产品信息
人参皂甙 Rc价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/01/25 | HY-N0042 | 人参皂甙 Rc Ginsenoside Rc | 11021-14-0 | 5mg | 700元 |
| 2024/01/25 | HY-N0042 | 人参皂甙 Rc Ginsenoside Rc | 11021-14-0 | 10mg | 1200元 |
| 2024/01/25 | HY-N0042 | 人参皂甙 Rc Ginsenoside Rc | 11021-14-0 | 10 mM * 1 mLin DMSO | 1425元 |
常见问题列表
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TNF-α
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IL-1β
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Ginsenoside Rc, one of major Ginsenosides from Panax ginseng, enhances γ-aminobutyric acid (GABA) receptor A (GABA A )-mediated ion channel currents. Ginsenoside Rc enhances GABA-mediated ion currents in oocytes expressing the GABA A receptor. Ginsenoside Rc significantly inhibits the expression of macrophage-derived cytokines, such as TNF-α and IL-1β. Ginsenoside Rc also markedly suppresses the activation of TANK-binding kinase 1/IκB kinase ε/interferon regulatory factor-3 and p38/ATF-2 signaling in activated RAW264.7 macrophages, human synovial cells, and HEK293 cells. Ginsenoside Rc exerts its anti-inflammatory actions by suppressing TANK-binding kinase 1/IκB kinase ε/interferon regulatory factor-3 and p38/ATF-2 signaling. Ginsenoside Rc suppresses the nuclear translocation of phospho-ATF-2 and phospho-FRA-1, whereas the translocation of p65 at its peak time points (30 and 60 min) is not decreased by Ginsenoside Rc treatment. Ginsenoside Rc regulates the expression of the proinflammatory cytokine TNF-α, which is produced by macrophages, by suppressing AP-1 activation.