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Name Glycerol
CAS 56-81-5
EINECS(EC#) 200-289-5
Molecular Formula C3H8O3
MDL Number MFCD00675440
Molecular Weight 92.09
MOL File 56-81-5.mol

Chemical Properties

Appearance Glycerol is a viscous colorless or pale yellow, odorless, syrupy liquid.
Melting point  20 °C(lit.)
Boiling point  290 °C
density  1.25 g/mL(lit.)
vapor density  3.1 (vs air)
vapor pressure  <1 mm Hg ( 20 °C)
refractive index  n20/D 1.474(lit.)
FEMA  2525
Fp  320 °F
storage temp.  2-8°C
solubility  H2O: 5 M at 20 °C, clear, colorless
form  Viscous Liquid
pka 14.15(at 25℃)
Specific Gravity 1.265 (15/15℃)1.262
color  APHA: ≤10
Odor Odorless.
Stability: Stable. Incompatible with perchloric acid, lead oxide, acetic anhydride, nitrobenzene, chlorine, peroxides, strong acids, strong bases. Combustible.
PH Range 5.5 - 8
PH 5.5-8 (25℃, 5M in H2O)
explosive limit 2.6-11.3%(V)
Water Solubility  >500 g/L (20 ºC)
Sensitive  Hygroscopic
λmax λ: 260 nm Amax: 0.05
λ: 280 nm Amax: 0.04
JECFA Number 909
Merck  14,4484
BRN  635685

glycerin (glycerol; propanetriol) is a humectant used in moisturizers. It is water-binding and able to draw and absorb water from the air, thus helping the skin retain moisture. glycerin has been studied extensively for its hydrating abilities. Based on the data available, glycerin has been established as a good skin-moisturizing agent. At least part of its activity is attributed to its facilitating enzymatic reactions in the skin, thereby promoting corneocyte desquamation. glycerin also improves the spreading qualities of creams and lotions. It is a clear, syrupy liquid made by chemically combining water and fat that is usually derived from vegetable oil. Although glycerin has not been shown to cause allergies, it may be comedogenic and irritating to the mucous membranes when used in concentrated solutions.

CAS DataBase Reference 56-81-5(CAS DataBase Reference)
NIST Chemistry Reference 1,2,3-Propanetriol(56-81-5)
EPA Substance Registry System 56-81-5(EPA Substance)

Safety Data

Hazard Codes  F,Xn
Risk Statements 

R36:Irritating to the eyes.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R11:Highly Flammable.

Safety Statements 

S24/25:Avoid contact with skin and eyes .
S39:Wear eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .

RIDADR  UN 1282 3/PG 2
WGK Germany  1
RTECS  MA8050000
Autoignition Temperature 698 °F
HS Code  29054500
Safety Profile

Poison by subcutaneous route. Mildly toxic by ingestion. Human systemic effects by ingestion: headache and nausea or vomiting. Experimental reproductive effects. Human mutation data reported. A skin and eye irritant. In the form of mist it is a nuisance particulate and inhalation irritant. Combustible liquid when exposed to heat, flame, or powerful oxidizers. Mixtures with hydrogen peroxide are highly explosive. Ignites on contact with potassium permanganate, calcium hypochlorite. Mixture with nitric acid + sulfuric acid forms the explosive glyceql nitrate. Mixture with perchloric acid + lead oxide forms explosive perchlorate esters. Confined mixture with chlorine explodes if heated to 70-80'. Can react violently with acetic anhydride, aniline + nitrobenzene, Ca(OCl)2, Cr03,Cr203, F2 + PbO, phosphorus triiodide, ethylene oxide + heat, KMnO4, K2O2, AgClO4, Na2O2, NaH. Energetic reaction with sodium hydride. Mixture with nitric acid + hydrofluoric acid is a storage hazard due to gas evolution. To fight fire, use alcohol foam, CO2, dry chemical. When heated to decomposition it emits acrid smoke and fumes.

Hazardous Substances Data 56-81-5(Hazardous Substances Data)

Hazard Information

Material Safety Data Sheet(MSDS)

Questions And Answer