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7-Methylquinoline

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7-Methylquinoline Basic information
7-Methylquinoline Chemical Properties
  • Melting point:35-37 °C(lit.)
  • Boiling point:258 °C(lit.)
  • Density 1.061
  • refractive index 1.6070 to 1.6210
  • Flash point:>230 °F
  • form Viscous Liquid
  • pka5.44±0.14(Predicted)
  • Water Solubility <0.1 g/100 mL at 20 ºC
  • BRN 110317
  • Stability:Stable. Incompatible with strong oxidizing agents, strong acids. May be light sensitive.
  • InChIKeyKDYVCOSVYOSHOL-UHFFFAOYSA-N
  • CAS DataBase Reference612-60-2(CAS DataBase Reference)
  • NIST Chemistry ReferenceQuinoline, 7-methyl-(612-60-2)
  • EPA Substance Registry System7-Methylquinoline (612-60-2)
Safety Information
  • Hazard Codes Xi
  • Risk Statements 37/38-41
  • Safety Statements 26-39
  • WGK Germany 3
  • RTECS VC0560000
  • TSCA Yes
  • HS Code 29334900
MSDS
7-Methylquinoline Usage And Synthesis
  • Chemical Propertieswhite to light yellow crystal powder
  • General Description7-Methylquinoline is a reagent used in the preparation of diarylmethylpiperazines as potent opioid receptor agonists with improved side effects. Also used in the preparation of novel pyrazine compounds derived from 2-phenylquinolin-7-yl which act as potent insulin-like growth factor-I receptor inhibitors.
  • Air & Water ReactionsInsoluble in water.
  • Reactivity Profile7-Methylquinoline may be sensitive to exposure to light. May react vigorously with strong oxidizing agents and strong acids . Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
  • Fire Hazard7-Methylquinoline is combustible.
  • Purification MethodsPurify it via its dichromate complex (m 149o, after five recrystallisations from water). [Cumper et al. J Chem Soc 1176 1962, Beilstein 20 III/IV 3497, 20/7 V 402.]
7-Methylquinoline Preparation Products And Raw materials
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