122548-33-8

The pure product is white crystals. Its mp is 183-184°C (decomposition), relative density is 1.574 (25°C), vapor pressure is 4.52×10-2 Pa (25°C), and dissociation constant pKa is 4. Its solubility in organic solvents at 25°C is: dichloromethane 12.8 g/L, acetone 7.6 g/L, acetonitrile 2.5 g/L, ethyl acetate 2.2 g/L, and xylene 400 mg/L. Its solubility in water is 308 mg/L (pH=7), 67 mg/L (pH=6.1), and 5 mg/L (pH=5.1). Its partition coefficient is 0.05.

Herbicide.

ChEBI: Imazosulfuron is an imidazopyridine.

The industrial synthesis of imazosulfuron begins with the preparation of two key intermediates: 2-chloroimidazo[1,2-a]pyridine-3-sulfonyl chloride and 4,6-dimethoxypyrimidin-2-amine. The process starts with chlorination and sulfonation of imidazo[1,2-a]pyridine to introduce the sulfonyl chloride group, which is essential for herbicidal activity. This intermediate is then reacted with the pyrimidine amine derivative in a condensation step to form the sulfonylurea linkage, a hallmark of this herbicide class. Reaction conditions such as temperature, solvent type, and pH are carefully controlled to ensure high yield and purity.

Inhibits plant growth, absorbed through roots and translocated throughout the plant. Inhibits plant amino acid synthesis - acetohydroxyacid synthase AHAS

Herbicide