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7803-58-9

Name Sulfamide
CAS 7803-58-9
EINECS(EC#) 232-262-9
Molecular Formula H4N2O2S
MDL Number MFCD00011606
Molecular Weight 96.11
MOL File 7803-58-9.mol
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Chemical Properties

Appearance White Solid
Melting point  90-92 °C(lit.)
density  1.611 g/mL at 25 °C(lit.)
storage temp.  Inert atmosphere,Room Temperature
solubility  water: soluble50mg/mL, clear, colorless to faintly yellow
form  Crystalline Powder, Free From Visible Impurities
pka 10.87±0.60(Predicted)
color  White to practically white , free from visible impurities
PH 5.67 at 21.7℃ and 10g/L
Water Solubility  soluble
Sensitive  Moisture Sensitive
Usage A carbonic anhydrase inhibitor; used for treatment of cancer.
Merck  14,8922
InChIKey NVBFHJWHLNUMCV-UHFFFAOYSA-N
Uses
Sulfamide and its derivatives can also be used to prepare fused thiadiazine systems, Reaction with 2-aminoacetophenones affords IH-2,1,3-benzothia- diazine 2,2-dioxides 77 (65JOC3960). The corresponding 3,4-dihydro deriv- atives are readily available from 2-aminobenzylamines with either sulfuryl chloride (70M1443) or sulfamide (66USP3278532; 71MI055). These kinds of compounds can also be obtained from N-aryl-N'-alkylsulfamides and s-trioxane in a reaction involving cyclization by intramolecular sulfamido- methylation (79JOC2032) (Scheme 30).
CAS DataBase Reference 7803-58-9(CAS DataBase Reference)
NIST Chemistry Reference Sulfamide(7803-58-9)
EPA Substance Registry System 7803-58-9(EPA Substance)

Safety Data

Hazard Codes  Xi
Risk Statements 
R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Statements 
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection .
WGK Germany  3
F  9
TSCA  Yes
HazardClass  IRRITANT
HS Code  28530090

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