113118-81-3

5-Bromo-3-pyridinecarboxaldehyde can be used as a pharmaceutical and chemical synthesis intermediate. In the existing technology, its synthesis method is to use 3,5-dibromo pyridine as raw material and exchange it with butyllithium bromide under ultra-low temperature (-78°C) conditions to prepare 5-Bromo-3-pyridinecarboxaldehyde. Or use 3,5-dibromopyridine as raw material and combine butyllithium and n-butylmagnesium chloride at -15°C to synthesize the product.