Алюминия калия сульфат додекагидра

Химические свойства

white to colourless crystals

Использование

Aluminium potassium sulfate dodecahydrate is a white crystal that is soluble in water. It is made by roasting alunite in a furnace and then harvesting the product by crystallization. Aluminium potassium sulfate dodecahydrate was used to harden gelatin emulsions by introduction, by bathing the exposed plates prior to development, or by use in the fixing bath. Mixed with citric or other acids, it was also used as a clearing bath to remove developer stains in negatives.

Определение

ChEBI: A hydrate resulting from the the formal combination of anhydrous potassium aluminium sulfate with 12 mol eq. of water.

Методы производства

Potassium alum is manufactured by treating bauxite with sulfuric acid and then potassium sulfate. Alternatively, aluminum sulfate is reacted with potassium sulfate.

Общее описание

Aluminum potassium sulfate dodecahydrate is an inorganic sulfate salt of aluminum and potassium. Linear growth rates of (100), (111) and (110) faces of its crystals have been investigated.

Угроза здоровью

Prolonged periods of exposure to aluminum and dust cause symptoms of toxicity that include, but are not limited to, coughing, wheezing, shortness of breath, memory loss, learning diffi culty, loss of coordination, disorientation, mental confusion, colic, heartburn, fl atulence, and headaches. Chronic exposures to alumina dust cause irritation to the eyes,

Фармацевтические приложения

Potassium alum precipitates proteins and is a powerful astringent. The ability to precipitate proteins is utilized in the manufacture of vaccines, where purified proteins are coprecipitated with and adsorbed onto potassium alum.
Potassium alum is often included in preparations used as mouthwashes or gargles and in dermatological preparations, and it may be used as a topical hemostatic, either as a solid or as a solution. Intravesical instillation of potassium alum, typically as a 1% solution, has been used for hemorrhagic cystitis.

Безопасность

Potassium alum is often included in preparations used as mouthwashes or gargles and in dermatological preparations.
Large doses of potassium alum act as an irritant and may be corrosive; gum necrosis and gastrointestinal hemorrhage have occurred. Acute encephalopathy has been reported following bladder irrigation with alum solutions in the treatment of bladder hemorrhage. Anecdotal evidence suggests that this practice should be avoided for patients with renal insufficiency.

хранилище

Store in a cool, dry place in tightly closed containers. Stable under normal temperatures and pressures. When kept for a long time at 60–65°C (or over sulfuric acid) potassium alum dodecahydrate loses water, which is reabsorbed on exposure to air. It becomes anhydrous at about 200°C.

Методы очистки

Crystallise it from weak aqueous H2SO4 (ca 0.5mL/g). Its solubility (%) in H2O is 5.7 (0o), 12.0 (20o) and 136.9 (100o).

Несовместимости

Potassium alum is incompatible with strong oxidizing agents, aluminum, copper, steel, and zinc. When it is dispensed in powders with phenol, salicylates, or tannic acid, gray or green colors may be developed owing to traces of iron in the alum.

Меры предосторожности

Aminocarb decomposes on heating and produces toxic fumes, irritating fumes, and oxides of nitrogen. During handling of aminocarb workers should wear protective clothing, gloves, face shield, breathing protection and avoid open flames.

Регуляторный статус

GRAS listed. Included in the FDA Inactive Ingredients Database (vaginal; suppository). Included in medicines licensed in the UK.