CAS 2627-69-2 Weight Loss Sarms Powders Aicar Acadesine for Bodybuilding

CAS 2627-69-2 Weight Loss Sarms Powders Aicar Acadesine for Bodybuilding

 

Quick Info.

 

Product Name:AICAR SARM POWDER

CAS No:2627-69-2

Molecular Formula:C9H14N4O5

Molecular Weight:258.2

Assay:98% min

Quality Standard:USP/ISO9001

Appearance:White or almost white powder

Supply Ability:500-800kg/month

Storage:Store at 8℃-20℃, protect from moisture and light.

Related Products:S-23 Powder,SR9009 Powder

 

Description:

 

AICAR is a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle.In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes. Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase). The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.