Benzophenone imine

clear colorless to light yellow-brownish liquid

Useful in the preparation of nitrile ylide dimers.Benzophenone imine as ammonia surrogate. As intermediate material for synthesis of organic chemicals. Catalytic enantioselective alkylation of the benzophenone imine of glycine t-butyl ester using phosphazene (Schwesinger) bases and chiral quaternary ammonium salts yields either enantiomer of amino acid derivatives in excellent yield.

Benzophenone imine is useful in the preparation of nitrile ylide dimers.

Benzophenone imine is a multifunctional reagent in organic synthesis, its core role being as an ammonia equivalent and a protecting group for primary amines. It reacts with primary amines to form stable Schiff bases, thereby protecting the functional groups of primary amines and preventing them from undergoing side reactions in subsequent reactions.

Synthetic Communications, 18, p. 1501, 1988 DOI: 10.1080/00397918808081307

Not classified