1,3,5-Trifluorobenzene

In a reaction flask, solvent, anhydrous potassium fluoride, a phase transfer catalyst, and crude 1,3,5-trichlorobenzene were added. The mixture was heated to reflux and reacted for 6-14 hours. After the reaction was complete, the solvent was removed by vacuum distillation, and the residue was subjected to steam distillation with water. The distillate was extracted with petroleum ether (60-90℃), and after removing the petroleum ether by rotary evaporation, the target compound 1,3,5-trifluorobenzene was collected by vacuum distillation.

Figure 1,3,5-trifluorobenzene synthesis reaction formula

CLEAR COLOURLESS LIQUID

1,3,5-Trifluorobenzene was used in the synthesis of (-)-epicatechin and its 3-O-gallate. It is also used as an intermediate in organic chemical synthesis.

1,3,5-Trifluorobenzene was used in the synthesis of ()-epicatechin and its 3-O-gallate.

Rotational Raman spectra of 1,3,5-trifluorobenzene has been studied under high resolution using a single mode argon laser as the exciting source. Proton and fluorine magnetic resonance spectra of 1,3,5-trifluorobenzene in a nematic liquid crystal has been analyzed.