N-Ethyl-N-hydroxyethylaniline

75-21-8

103-69-5

92-50-2

1. The autoclave was purged with nitrogen and protected by nitrogen with 24.2 kg (200 mol) of N-ethylaniline, 8.9 kg (202 mol) of ethylene oxide, and 242 g (1.9 mol) of taurine. 2. The autoclave was closed, making sure that the lid was screwed on tightly. 3. The heating system was turned on, and the temperature was ramped up to 102°C at a rate of 1°C/min before stopping the heating, and the temperature of the reaction will naturally rise to 133°C. 4. Maintain the reaction at 133°C for 4 h. 5. Upon completion of the reaction, the reaction mixture was cooled to 40°C. 6. Open the autoclave and collect the product to give 32.8 kg of N-ethyl-N-hydroxyethylaniline in 99.4% yield.