Basic information Antiestrogen drug Origin of the study Uses Pharmacokinetics Side effects Contraindications Precautions Drug interactions Safety Related Supplier
Tamoxifen Structure

Tamoxifen

Chemical Properties

Melting point 97-98 °C(lit.)
Boiling point 501.18°C (rough estimate)
Density  1.0630 (rough estimate)
vapor pressure  0Pa at 25℃
refractive index  1.6000 (estimate)
storage temp.  2-8°C
solubility  H2O: insoluble <0.1% at 20°C
pka pKa 8.71(H2O t = 25 I = 0.025) (Uncertain)
color  Crystals from pet ether
Water Solubility  Insoluble in water. Soluble in methanol, ethanol, propanol or propylene glycol.Soluble in dimethyl sulfoxide, dichloromethane and ethanol. Insoluble in water.
Merck  13,9137
Stability Light Sensitive
InChIKey NKANXQFJJICGDU-QPLCGJKRSA-N
LogP 6.3 at 20℃
CAS DataBase Reference 10540-29-1(CAS DataBase Reference)
IARC 1 (Vol. 66, 100A) 2012
EPA Substance Registry System Tamoxifen (10540-29-1)

Safety Information

Hazard Codes  T,Xi
Risk Statements  45-60-61-64-36/37/38
Safety Statements  53-45-36-26
WGK Germany  3
RTECS  KR5919600
HS Code  29221990
Hazardous Substances Data 10540-29-1(Hazardous Substances Data)
Toxicity LD50 orl-rat: 4100 mg/kg DRFUD4 9,186,84

MSDS

Usage And Synthesis

Preparation Products And Raw materials

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Tamoxifen manufacturers