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MK-1775

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MK-1775 Basic information
MK-1775 Chemical Properties
  • Boiling point:723.8±70.0 °C(Predicted)
  • Density 1.292
  • pka13.27±0.29(Predicted)
MK-1775 Usage And Synthesis
  • DescriptionMK-1775 is a small molecule inhibitor of the tyrosine kinase WEE1 with potential antineoplastic sensitizing activity. MK-1775 selectively targets and inhibits WEE1, a tyrosine kinase that phosphorylates cyclin-dependent kinase 1 (CDK1, CDC2) to inactivate the CDC2/cyclin B complex. Inhibition of WEE1 activity prevents the phosphorylation of CDC2 and impairs the G2 DNA damage checkpoint. This may lead to apoptosis upon treatment with DNA damaging chemotherapeutic agents. MK-1775 is a type of biological therapy. It is a cancer growth blocker. It stops signals that cancer cells use to divide and grow. MK-1775 has been used in trials studying the treatment of LYMPHOMA, Neoplasms, Ovarian Cancer, Tongue Carcinoma, and Adult Glioblastoma, among others.
MK-1775(955365-80-7)Related Product Information
MK-1775SupplierMore
  • Company Name:Artis Biotech Co. Ltd. Gold
  • Tel:13918153394 0575-89298960 +91-8849247288
  • Email:sales@artis-standards.com;jkansara@artis-standards.com
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  • Company Name:WuHu Linze pharmaceutical Co.,Ltd. Gold
  • Tel:18356571950
  • Email:2030235803@qq.com
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  • Company Name:Shanghai Drjart Biological Co., Ltd. Gold
  • Tel:18616739945
  • Email:drjartchem@sina.com
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  • Company Name:Wuhan Shuangjin Fine Chemical Co., Ltd. Gold
  • Tel:15926256169
  • Email:773164315@qq.com;
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  • Company Name:Ningbo Risheng Pharmaceutical Technology Co., Ltd. Gold
  • Tel:19906600019
  • Email:2928184953@qq.com
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