White crystalline powder, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from citrus.
Sinensetin exhibits anti-fungal, anti-histamine activity; induce cell differentiation, inhibition of linoleic acid oxidation, inhibition of white blood cells in the human zona protein Interleukin -1-i
nduced expression of tissue factor.
Sinensetin, eupatorin, 3'-hydroxy-5,6,7,4'-tetramethoxyflavone and rosmarinic acid contents and antioxidative effect of Orthosiphon stamineus from Malaysia.
antiangiogenesis, antidiabetic
ChEBI: A pentamethoxyflavone that is flavone substituted by methoxy groups at positions 5, 6, 7, 3' and 4' respectively.
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Sinensetin is a citris flavonoid with anti-inflammatory and anti-proliferative activity. It has also been shown to enhance adipogenesis and lipolysis.
Sinensetin (50 mg/kg, single dose, i.p.) has anti-inflammatory effects on carrageenan (HY-125474) induced paw inflammation in the mouse[5].
| Animal Model: | Carrageenan-induced paw edema in male C57BL/6 mice[5] |
| Dosage: | 50 mg/kg, single dose |
| Administration: | Intraperitoneal injection (i.p.) |
| Result: | Sloewd the volume increased of the carrageenan-treated paw at 6 h. |
