3,4,5-Trimethoxybenzoic acid is an important fine chemical product or pharmaceutical intermediate, which is widely used in the fields of medicine, dye, food and fine chemical industry.
3,4,5-trimethoxybenzoic acid can be synthesised by methoxylation of gallic acid and dimethyl sulfate, and the fine product is obtained after neutralization, filtration and washing.
3,4,5-Trimethoxy benzoic acid is a white to beige fine crystalline powder.
3,4,5-Trimethoxybenzoic acid is used as intermediates in medicine and organic synthesis. It acts as a metabolite of trimebutine. It is widely used in making dyes and inks, photographic developers and used as astringents in medically.
A metabolite of Trimebutine (T795605).
ChEBI: A benzoic acid derivative carrying 3-, 4- and 5-methoxy substituents.
Research found that 3,4,5-Trimethoxy benzoic acid showed strong antioxidative activity in DPPH free radical scavenging assay[1].
[1] Wang, Y. C., Wang, H. M. D., Liu, S. L., Chen, C. Y. (2024). Metabolites from Smilax nantoensis with Antioxidant Activity. Chemistry of Natural Compounds, 60 2, 320–323.
https://doi.org/10.1007/s10600-024-04314-6