ChemicalBook Product Catalog Analytical Chemistry Standard Food and beverage standards 2-Ethylhexyl salicylate

2-Ethylhexyl salicylate

Product Name2-Ethylhexyl salicylate
CAS118-60-5
MFC15H22O3
MW250.33
EINECS204-263-4
MOL File118-60-5.mol

Chemical Properties

Boiling point	189-190 °C/21 mmHg (lit.)
Density	1.014 g/mL at 25 °C (lit.)
vapor pressure	0.018Pa at 20℃
refractive index	n20/D 1.502(lit.)
Flash point	>230 °F
storage temp.	Refrigerator
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly)
pka	8.13±0.30(Predicted)
form	Liquid
color	A colourless liquid.
Odor	at 100.00 %. mild orchid sweet balsam
Odor Type	floral
biological source	synthetic
Water Solubility	74.4μg/L at 20℃
Merck	14,6770
BRN	2730664
Major Application	cleaning products cosmetics environmental flavors and fragrances food and beverages personal care
Cosmetics Ingredients Functions	LIGHT STABILIZER UV ABSORBER UV FILTER
Cosmetic Ingredient Review (CIR)	2-Ethylhexyl salicylate (118-60-5)
InChI	1S/C15H22O3/c1-3-5-8-12(4-2)11-18-15(17)13-9-6-7-10-14(13)16/h6-7,9-10,12,16H,3-5,8,11H2,1-2H3
InChIKey	FMRHJJZUHUTGKE-UHFFFAOYSA-N
SMILES	CCCCC(CC)COC(=O)c1ccccc1O
LogP	5.94 at 25℃
CAS DataBase Reference	118-60-5(CAS DataBase Reference)
NIST Chemistry Reference	Salicylic acid, 2-ethylhexyl ester(118-60-5)
EPA Substance Registry System	2-Ethylhexyl salicylate (118-60-5)

Safety Information

Risk Statements	36/37/38
Safety Statements	26-36/37/39
WGK Germany	-
RTECS	VO3150000
TSCA	TSCA listed
HS Code	2918230000
Storage Class	10 - Combustible liquids
Hazard Classifications	Aquatic Chronic 1
Toxicity	LD50 intraperitoneal in mouse: 200mg/kg

MSDS

Provider	Language
SigmaAldrich	English

Usage And Synthesis

Chemical Properties

liquid

Occurrence

Has apparently not been reported to occur in nature.

Uses

ethylhexyl salicylate is an FDA-approved uVB sunscreen chemical, it absorbs within the entire uVB range. It has an approved usage level of 3 to 5 percent in both the united States and the european union, and is a good solubilizer for benzophenone-3. In suntan lotions, it is used as a preservative and anti-microbial. This is a salt of salicylic acid occurring in wintergreen leaves and in other plants. It is also synthetically manufactured. It is considered a non-comedogenic raw material. This is the InCI name for octyl salicylate.

Uses

Solvent for solid sunscreens.

Uses

octisalate is a uVB protector. This is the drug name for ethylhexyl salicylate and octyl salicylate.

Uses

2-ethylhexyl salicylate is also known as ethylhexyl salicylate and octyl salicylate. It is a uVB absorber.

Preparation

From 2-ethylhexanol and salicylic acid by azeotropic-type esterification (Arctander, 1969).

Definition

ChEBI: Ethylhexyl salicylate is a benzoate ester and a member of phenols. It is functionally related to a salicylic acid.

brand name

Escalol (ISP Van Dyk); Neo Heliopan (Haarmann & Reimer, Germany); Uvinul (BASF). Note—The International Cosmetic Ingredient (INCI) name for octisalate is octyl salicylate.

General Description

2-Ethylhexyl salicylate(EHS) is an organic ultraviolet(UV) absorber that can be used as a photostable ingredient in cosmetic formulations. It shows an absorption spectra in the range of 280-320 nm in the UV region.

Flammability and Explosibility

Non flammable