DOTP can form a composite blend with polyaniline (PANI)-ethyene dimethacrylate (EDMA), which can be used in the fabrication of conductive films. It may also be used as a plasticizer with polyvinyl chloride (PVC) to form solutions for artificial intravessel plaque.
It is used primarily as a plasticizer
for polyvinyl chloride and other polymers.
DEHT is manufactured by the esterification of terephthalic
acid and 2-ethylhexanol.
Dioctyl terephthalate (DOTP) is a plasticizer that can be prepared by alcoholysis of polyethylene terephthalate (PET) with isooctyl alcohol.
The carcinogenic potential of
DEHT was evaluated in a 2-year study in which male and
female rats were given diets containing 1500, 6000, or 12,000
ppm. There was no effect on tumor incidence, and
therefore, the NOEL for tumorigenicity was at least
12,000 ppm (equivalent to 666 mg/kg/day in males and
901 mg/kg/day in females).
