苯赖加压素
苯赖加压素 性质
| 熔点 | >197oC (dec.) |
|---|---|
| 沸点 | 1571.3±65.0 °C(Predicted) |
| 密度 | 1.288±0.06 g/cm3(Predicted) |
| 储存条件 | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| 溶解度 | 易溶于水，几乎不溶于丙酮和乙醇（96%）。溶于碱金属氢氧化物的稀溶液。 |
| 酸度系数(pKa) | 12.82±0.70(Predicted) |
| 形态 | 固体 |
| 颜色 | 白色 |
| 序列 | H-[Cys-Phe-Phe-Gln-Asn-Cys]-Pro-Lys-Gly-NH2，(Disulfide bridge: Cys-Cys) |
| CAS 数据库 | 56-59-7(CAS DataBase Reference) |
苯赖加压素 用途与合成方法
Vasopressin 1
Felypressin is a synthetic hormone of the posterior pituitary lobe characterized by vasoconstrictor properties that is widely used in dental procedures. The vasoconstrictor action of Felypressin seems to be mediated by V1 receptors of the blood vessel smooth muscle cells.
Felypressin can reduce toxicity during dental procedures. Felypressin increases the diastolic blood pressure of hypertensive patients with controlled blood pressure.
Cardiovascular effects of Felypressin (240 ng/kg; intravenous injection) are studied in Wistar rats. Felypressin induces a pressor effect. Felypressin depends on V1 receptors to induce pressor and bradycardic effects, and that it produces a high relationship between bradycardia and mean arterial pressure variation depending on area postrema and central V1 receptors.
单杂≤1.0%
醋酸根含量5.0%～12.0%
水分含量≤10.0%
肽含量≥80.0%
不良反应和禁忌：用药后可有面色和皮肤苍白、尿意、腹痛、腹泻、脉搏减慢等症状；过量会恶心、呕吐。冠状动脉患者忌用，孕妇和老人慎用。
苯赖加压素 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024-11-08 | HY-A0182A | 苯赖加压素 | 56-59-7 | 5 mg | 500 |
| 2024-11-08 | HY-A0182A | 苯赖加压素 | 56-59-7 | 10 mg | 800 |
