(R)-3-Amino-1-Boc-piperidine can be used to prepare a benzoxazepine derivative named (R)-7-(3,5-dimethoxyphenyl)-N-(piperidin-3-yl)-4-propionyl-2,3,4,5-tetrahydro-1,4-benzoxazepine-9-carboxamide, a potent CBP/P300 bromodomain inhibitor.
(R)-(-)-3-Amino-1-Boc-piperidine(tert-Butyl (R)-3-Aminopiperidine-1-carboxylate), is an heterocyclic building block used for the synthesis of more complex pharmaceutical compounds. It is also found to act as a γ-secretase modulators, and a potent structure for lowering Ab42 production in both in vitro and in vivo.
(R)-3-Amino-1-Boc-piperidine can be used as a precursor for the preparation of dipeptidyl peptidase IV inhibitors like linagliptin, alogliptin, and other antidiabetic agents.
