2-吲哚酮
2-吲哚酮 性质
熔点 | 123-128 °C(lit.) |
---|---|
沸点 | 227 °C73 mm Hg(lit.) |
密度 | 1.1475 (rough estimate) |
折射率 | 1.5282 (estimate) |
闪点 | 194-196°C/17mm |
储存条件 | Sealed in dry,Room Temperature |
溶解度 | 9.1g/l |
形态 | 固体 |
酸度系数(pKa) | 14.77±0.20(Predicted) |
颜色 | 浅棕色 |
水溶解性 | insoluble |
BRN | 114692 |
CAS 数据库 | 59-48-3(CAS DataBase Reference) |
NIST化学物质信息 | 2H-Indol-2-one, 1,3-dihydro-(59-48-3) |
EPA化学物质信息 | Oxindol (59-48-3) |
2-吲哚酮 用途与合成方法
Oxindole (Indolin-2-one) is a bicyclic structure consisting of a benzene ring fused to 2-pyrrolidone. Substituted indolinones can be referred as ‘privileged structures’ owing to their excellent binding affinity for many receptors and to the number of approved drugs containing this scaffold. Oxindole has been found in tissues and fluids of mammals as well as natural products produced by a range of plants, bacteria and invertebrates. 2-indolinone derivatives possess diverse range of pharmacological activities including anti-cancer, anti-HIV, anti-diabetic, antibacterial, antioxidant, kinase inhibitory, AChE inhibitory, anti-leishmanial, b3 adrenergic receptor agonistic, phosphatase inhibitory, analgesic, spermicidal, vasopressin antagonists, progesterone antagonists, neuroprotection, NMDA blocker and sleep inducing activities.
吲哚类似物; 显示药理活性。
安全信息
危险品标志 | Xn |
---|---|
危险类别码 | 22 |
安全说明 | 22-24/25 |
危险品运输编号 | 2811 |
WGK Germany | 3 |
RTECS号 | NM2080500 |
危险等级 | 6.1(b) |
包装类别 | III |
海关编码 | 29337900 |
MSDS信息
2-吲哚酮 价格(试剂级)
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
---|---|---|---|---|---|
2024-11-11 | XW00594833 | 2-吲哚酮 | 59-48-3 | 100G | 295 |
2024-11-11 | XW00594832 | 2-吲哚酮 | 59-48-3 | 25G | 76 |