WHITE TO OFF-WHITE CRYSTALLINE POWDER
Acetanilide is used as an inhibitor of peroxides and?stabilizer for cellulose ester varnishes.?It is used as an intermediate for the synthesis of?rubber accelerators, dyes and dye intermediate and camphor. It is used as a precursor in penicillin synthesis and other pharmaceuticals including painkillers and intermediates.
o-Methylacetanilide is a substituted acetanilide that is used as precursor for various pharmaceuticals including their intermediates.
ChEBI: 2`-Methylacetanilide is a member of toluenes.
Journal of the American Chemical Society, 106, p. 5759, 1984
DOI: 10.1021/ja00331a073Organic Syntheses, Coll. Vol. 5, p. 650, 1973
Colorless crystals. Insoluble in water.
2-METHYLACETANILIDE is an amide. Amides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
ACUTE/CHRONIC HAZARDS: Toxic. Hazardous decomposition products.
Moderately toxic by ingestion.Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
Crystallise the toluidide from hot H2O (solubility 1g/210mL), EtOH or aqueous EtOH. UV: max 230 and 280nm (EtOH). [Beilstein 12 H 792, 12 I 376, 12 II 439, 12 III 1853, 12 IV 1755.]
