Procaterol hydrochloride hemihydrate (1, 3 or 10 μg/mL, inhaled administration) inhibits histamine-induced airflow obstruction and microvascular leakage in guinea-pig airways with allergic inflammation[2].
Procaterol hydrochloride hemihydrate (0.1 mg/kg, i.p.) completely abolishes both the Mch-induced cough in conscious guinea pigs[3].
| Animal Model: | Allergic inflammatory guinea-pig model[2] |
| Dosage: | 1, 3 or 10 μg/mL |
| Administration: | Inhaled administration |
| Result: | Inhibited histamine-induced airflow obstruction and microvascular leakage. |