clear yellow to green-yellow liquid
2'',5''-Dimethoxyacetophenone is a useful building block which has been used in the preparation of pyridine and thieno[2,3-b] pyridine derivatives as anticancer PIM-1 kinase inhibitors, and in the synthesis of anti-cancer and apoptosis-inducing agents.
Obtained by reaction of dimethyl sulfate with quinacetophenone in the presence of 10% aqueous sodium hydroxide.
2',5'-Dimethoxyacetophenone is prepared from Hydroquinone dimethylether and Acetic anhydride with Aluminum chloride catalyst.
